
Domperidone (30mg) + Rabeprazole (20mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Nuloc-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the management of gastrointestinal disorders characterized by acid-related symptoms and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcer disease. The sustained-release formulation of Nuloc-D ensures a prolonged therapeutic effect, enhancing patient compliance by reducing dosing frequency. This combination is particularly beneficial in patients with concomitant motility disorders and acid hypersecretion, offering symptomatic relief and promoting mucosal healing. Nuloc-D Capsule SR should be administered as prescribed by a healthcare professional, with caution in patients with known hypersensitivity to its components, hepatic or renal impairment, or underlying cardiac conditions. Regular monitoring and adherence to recommended dosage are essential to minimize potential adverse effects and optimize therapeutic outcomes.
How to use Nuloc-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nuloc-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Nuloc-D Capsule SR. Please consult your doctor.
High Risk
Nuloc-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Nuloc-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Nuloc-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Nuloc-D Capsule SR may be needed. Please consult your doctor. Use of Nuloc-D Capsule SR is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Nuloc-D Capsule SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Nuloc-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Nuloc-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Nuloc-D Capsule SR

Domperidone (30mg) + Rabeprazole (20mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Nuloc-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the management of gastrointestinal disorders characterized by acid-related symptoms and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcer disease. The sustained-release formulation of Nuloc-D ensures a prolonged therapeutic effect, enhancing patient compliance by reducing dosing frequency. This combination is particularly beneficial in patients with concomitant motility disorders and acid hypersecretion, offering symptomatic relief and promoting mucosal healing. Nuloc-D Capsule SR should be administered as prescribed by a healthcare professional, with caution in patients with known hypersensitivity to its components, hepatic or renal impairment, or underlying cardiac conditions. Regular monitoring and adherence to recommended dosage are essential to minimize potential adverse effects and optimize therapeutic outcomes.
How to use Nuloc-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nuloc-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Nuloc-D Capsule SR. Please consult your doctor.
High Risk
Nuloc-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Nuloc-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Nuloc-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Nuloc-D Capsule SR may be needed. Please consult your doctor. Use of Nuloc-D Capsule SR is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Nuloc-D Capsule SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Nuloc-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Nuloc-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Nuloc-D Capsule SR















