Nublexa Tablet
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Strip of 28 tablets • TabletPrescription requiredSchedule H
Nublexa Tablet
Regorafenib (40mg)
₹36965.00
Strip of 28 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Regorafenib 40 mg
How It Works
Regorafenib inhibits multiple tyrosine kinases, disrupting signaling pathways that promote tumor growth and angiogenesis.
Medicine Strength
40 mg
Uses & Benefits
Medical applications
Blood PressureSkin
Nublexa Tablet contains Regorafenib 40 mg, a multi-kinase inhibitor used in the treatment of various malignancies. Regorafenib exerts its therapeutic effect by inhibiting multiple protein kinases involved in tumor angiogenesis, oncogenesis, and the tumor microenvironment, thereby reducing tumor growth and proliferation. Nublexa is primarily indicated for the treatment of metastatic colorectal cancer, gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma in patients who have previously received standard therapies.
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The recommended dosage and administration should be determined by a healthcare professional based on the patient’s condition and tolerance. Common adverse effects associated with Regorafenib include hypertension, hand-foot skin reaction, fatigue, diarrhea, and hepatotoxicity; therefore, regular monitoring of blood pressure, liver function tests, and other relevant parameters is essential during therapy.
Patients should be advised to report any unusual symptoms promptly. Nublexa should be used with caution in individuals with pre-existing liver impairment or cardiovascular conditions. It is contraindicated in pregnancy due to potential teratogenic effects. As with all anticancer agents, adherence to prescribed dosing schedules and close clinical supervision are critical to optimize therapeutic outcomes and minimize adverse effects.
Dosage & How to Use
Diarylethers Derivative
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Nublexa Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Pregnancy
Nublexa Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Nublexa Tablet is safe to use in patients with kidney disease. No dose adjustment of Nublexa Tablet is recommended. However, limited information is available on use of Nublexa Tablet in patients with severe kidney disease.
Exercise Caution
Breastfeeding
It is not known whether Nublexa Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Kidney
Nublexa Tablet should be used with caution in patients with liver disease. Dose adjustment of Nublexa Tablet may be needed. Please consult your doctor. Regular monitoring of liver function tests is advised while you are taking this medicine. Use of Nublexa Tablet is not recommended in patients with the severe liver disease.
Regular Checkup
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