Nexavar 200mg Tablet
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Sorafenib (200mg)
Bottle of 60 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Sorafenib inhibits multiple kinases involved in tumor growth and angiogenesis, blocking signals that promote cancer progression.
Medical applications
Nexavar 200mg Tablets contain Sorafenib, an orally active multi-kinase inhibitor. It is primarily indicated for the treatment of advanced renal cell carcinoma and hepatocellular carcinoma. Nexavar works by blocking multiple kinases involved in angiogenesis, cell proliferation, and apoptosis. The recommended dose is 400mg orally, twice daily, with meals. It should be taken continuously until disease progression or unacceptable toxicity occurs.
Common adverse reactions include hand-foot skin reaction, diarrhea, fatigue, and hypertension. Prothrombin time, blood pressure, and liver function should be regularly monitored during treatment. Use with caution in patients with significant cardiovascular disease, active bleeding, or severe hepatic impairment. Pregnant women should avoid handling crushed or broken tablets due to potential fetal toxicity.
Diarylethers Derivative
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Nexavar 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Nexavar 200mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Medical Advice
Nexavar 200mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Nexavar 200mg Tablet is recommended. Regular monitoring of blood tests may be advised while you are taking this medicine.
Exercise Caution
Nexavar 200mg Tablet does not usually affect your ability to drive.
Consult Doctor
Nexavar 200mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Nexavar 200mg Tablet may be needed. Please consult your doctor.
Regular Checkup
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