Nadtotal NP Tablet SR
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Pregabalin (75mg) + Nortriptyline (10mg)
1 units • Other
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Medical applications
Nadtotal NP Tablet SR is a combined pharmaceutical preparation, containing Pregabalin 75mg and Nortriptyline 10mg. This extended-release formulation is designed for twice-daily administration. Pregabalin, an anticonvulsant and analgesic, is primarily used for the management of neuropathic pain, generalized anxiety disorder, and fibromyalgia. Nortriptyline, a tricyclic antidepressant, is indicated for the treatment of major depressive disorder.
The combined use of these two agents may provide additional benefits in managing various neuropsychiatric conditions, such as neuropathic pain with depressive symptoms or anxiety comorbidities. As with any medication, it is crucial to adhere to the prescribed dosage and monitor for potential side effects or interactions with other medications. Consult a healthcare provider for proper use and dosage adjustments.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Nadtotal NP Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Nadtotal NP Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Nadtotal NP Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Nadtotal NP Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Nadtotal NP Tablet SR may cause side effects which could affect your ability to drive. As Nadtotal NP Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Nadtotal NP Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Nadtotal NP Tablet SR may be needed. Please consult your doctor.
Regular Checkup
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