Mithox PG 750mcg/75mg Capsule
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Methylcobalamin (750mcg) + Pregabalin (75mg)
Strip of 10 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Medical applications
Mithox PG 750mcg/75mg Capsule is a prescription-only medication comprising a fixed-dose combination of methylcobalamin (750mcg) and pregabalin (75mg). This innovative formulation offers a synergistic therapeutic approach for the management of peripheral neuropathic pain, particularly in patients with type 2 diabetes. Methylcobalamin, a vital co-factor in various enzyme reactions, is essential for the maintenance of myelin sheaths and neuronal function.
Its inclusion in Mithox PG helps to mitigate the effects of diabetic neuropathy, which is characterized by sensory loss, numbness, and pain. Pregabalin, a gamma-aminobutyric acid (GABA) analog, is a well-established agent for the treatment of neuropathic pain, acting by modulating the activity of voltage-gated calcium channels. The combination of these two agents in Mithox PG 750mcg/75mg Capsule provides a comprehensive approach to addressing the complex pathophysiology of diabetic neuropathic pain, offering improved efficacy and tolerability profiles compared to monotherapy with individual components.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Mithox PG 750mcg/75mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Mithox PG 750mcg/75mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Mithox PG 750mcg/75mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Mithox PG 750mcg/75mg Capsule may be needed. Please consult your doctor.
Exercise Caution
Mithox PG 750mcg/75mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Mithox PG 750mcg/75mg Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mithox PG 750mcg/75mg Capsule may not be needed in these patients. Please consult your doctor.
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