Methypro-NT Tablet SR
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1 units • Other
Methypro-NT Tablet SR
Pregabalin (75mg) + Nortriptyline (10mg)
₹150.00
1 units • Other
1
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Active composition
Nortriptyline 10 mg
+1 more active ingredient
How It Works
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Medicine Strength
10 mg
All Active Ingredients
Nortriptyline10 mg
Pregabalin75 mg
Uses & Benefits
Medical applications
Pain
Methypro-NT Tablet SR is a sustained-release formulation combining Pregabalin 75 mg and Nortriptyline 10 mg, designed for the management of neuropathic pain and certain chronic pain conditions. Pregabalin, an anticonvulsant agent, modulates calcium channels in the central nervous system, thereby reducing neurotransmitter release and alleviating neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic activity by inhibiting the reuptake of these neurotransmitters, contributing to analgesic effects and mood stabilization.
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The sustained-release formulation ensures a gradual release of active ingredients, promoting consistent plasma levels and improved patient compliance by reducing dosing frequency. Methypro-NT is indicated for conditions such as diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia, where conventional analgesics may be insufficient. It should be used under medical supervision, with dosage adjustments based on therapeutic response and tolerability.
Common adverse effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiac arrhythmias, renal impairment, or concomitant use of CNS depressants. Methypro-NT should not be abruptly discontinued to avoid withdrawal symptoms. Regular monitoring and adherence to prescribed dosing are essential for optimal therapeutic outcomes.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Methypro-NT Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Methypro-NT Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Methypro-NT Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Methypro-NT Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Breastfeeding
Methypro-NT Tablet SR may cause side effects which could affect your ability to drive. As Methypro-NT Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Kidney
Methypro-NT Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Methypro-NT Tablet SR may be needed. Please consult your doctor.
Regular Checkup
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