
Memantine (10mg) + Donepezil (5mg)
Active composition
+1 more active ingredient
Memantine selectively blocks NMDA receptors, modulating glutamate activity and preventing excitotoxicity, which contributes to neuronal damage.
Donepezil inhibits acetylcholinesterase, leading to increased acetylcholine availability at synapses and enhanced cholinergic transmission.
Medical applications
Menata-D Tablet contains a combination of Donepezil 5 mg and Memantine 10 mg, indicated for the management of moderate to severe Alzheimer's disease. Donepezil, a reversible acetylcholinesterase inhibitor, enhances cholinergic function by increasing the concentration of acetylcholine in the brain, thereby improving cognitive function and memory. Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, modulates glutamatergic neurotransmission by blocking excessive NMDA receptor activity, which is implicated in neurodegeneration. The synergistic action of these agents aims to slow cognitive decline and improve behavioral symptoms associated with Alzheimer's disease. Menata-D is prescribed to patients exhibiting significant cognitive impairment and functional decline, where monotherapy has proven insufficient. The combination therapy is generally well-tolerated, with common adverse effects including dizziness, headache, gastrointestinal disturbances, and fatigue. Caution is advised in patients with renal impairment, cardiovascular conditions, or a history of seizures. Dosage should be individualized based on clinical response and tolerability, with regular monitoring recommended to assess efficacy and safety. Menata-D Tablet should be used under medical supervision as part of a comprehensive treatment plan including non-pharmacological interventions.
How to use Menata-D Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Menata-D Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Menata-D Tablet.
High Risk
Menata-D Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Menata-D Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Menata-D Tablet should be used with caution in patients with liver disease. Dose adjustment of Menata-D Tablet may be needed. Please consult your doctor.
Regular Checkup
Information regarding the use of Menata-D Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Menata-D Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Menata-D Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Menata-D Tablet

Donepezil (5mg) + Memantine (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Memantine selectively blocks NMDA receptors, modulating glutamate activity and preventing excitotoxicity, which contributes to neuronal damage.
Donepezil inhibits acetylcholinesterase, leading to increased acetylcholine availability at synapses and enhanced cholinergic transmission.
Medical applications
Menata-D Tablet contains a combination of Donepezil 5 mg and Memantine 10 mg, indicated for the management of moderate to severe Alzheimer's disease. Donepezil, a reversible acetylcholinesterase inhibitor, enhances cholinergic function by increasing the concentration of acetylcholine in the brain, thereby improving cognitive function and memory. Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, modulates glutamatergic neurotransmission by blocking excessive NMDA receptor activity, which is implicated in neurodegeneration. The synergistic action of these agents aims to slow cognitive decline and improve behavioral symptoms associated with Alzheimer's disease. Menata-D is prescribed to patients exhibiting significant cognitive impairment and functional decline, where monotherapy has proven insufficient. The combination therapy is generally well-tolerated, with common adverse effects including dizziness, headache, gastrointestinal disturbances, and fatigue. Caution is advised in patients with renal impairment, cardiovascular conditions, or a history of seizures. Dosage should be individualized based on clinical response and tolerability, with regular monitoring recommended to assess efficacy and safety. Menata-D Tablet should be used under medical supervision as part of a comprehensive treatment plan including non-pharmacological interventions.
How to use Menata-D Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Menata-D Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Menata-D Tablet.
High Risk
Menata-D Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Menata-D Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Menata-D Tablet should be used with caution in patients with liver disease. Dose adjustment of Menata-D Tablet may be needed. Please consult your doctor.
Regular Checkup
Information regarding the use of Menata-D Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Menata-D Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Menata-D Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Menata-D Tablet















