Melcyl 10mg Tablet
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Methoxsalen (10mg)
Strip of 10 tablets • Tablet
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Active composition
Methoxsalen intercalates into DNA and, upon exposure to UVA light, induces apoptosis in rapidly dividing skin cells.
Medical applications
Melcyl 10mg Tablet contains Methoxsalen, a psoralen derivative used primarily in the treatment of skin disorders such as vitiligo and psoriasis. Methoxsalen acts by intercalating into DNA and, upon exposure to ultraviolet A (UVA) light, forms cross-links that inhibit DNA synthesis and cellular proliferation. This mechanism helps to restore pigmentation in vitiligo and reduce hyperproliferation in psoriatic lesions.
Melcyl 10mg is typically administered orally prior to UVA phototherapy sessions, with the timing and dosage carefully adjusted by healthcare professionals to optimize therapeutic outcomes while minimizing adverse effects. The medication requires strict adherence to UVA exposure guidelines to prevent phototoxic reactions. Common side effects may include nausea, headache, dizziness, and photosensitivity.
Long-term use necessitates regular monitoring due to the potential risk of phototoxicity and increased susceptibility to skin malignancies. Melcyl 10mg should be used under medical supervision, with contraindications including hypersensitivity to Methoxsalen, pregnancy, and certain hepatic or renal impairments. Patients are advised to avoid excessive sunlight and use protective measures during treatment.
This medication represents an effective adjunct in photochemotherapy protocols for select dermatological conditions.
Psoralens Derivative
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Melcyl 10mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Melcyl 10mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Medical Advice
There is limited information available on the use of Melcyl 10mg Tablet in patients with kidney disease. Please consult your doctor.
Exercise Caution
It is not known whether Melcyl 10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Melcyl 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Melcyl 10mg Tablet may be needed. Please consult your doctor.
Regular Checkup
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