
Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w) + Hydroquinone (2% w/w)
Active composition
+2 more active ingredients
Tretinoin increases cell turnover and decreases sebum production, preventing the formation of acne lesions.
Fluocinolone Acetonide binds to glucocorticoid receptors, modulating gene expression and inhibiting the inflammatory response.
Hydroquinone inhibits the enzyme tyrosinase, reducing melanin synthesis and lightening hyperpigmented skin.
Medical applications
Melanorm-F Cream is a topical formulation containing Hydroquinone (2% w/w), Tretinoin (0.025% w/w), and Fluocinolone acetonide (0.01% w/w), indicated for the treatment of melasma and other hyperpigmentation disorders. Hydroquinone acts as a depigmenting agent by inhibiting tyrosinase, thereby reducing melanin synthesis and promoting skin lightening. Tretinoin, a retinoid, facilitates increased skin cell turnover and enhances the penetration of hydroquinone, contributing to the effective resolution of hyperpigmented lesions. Fluocinolone acetonide, a mild corticosteroid, provides anti-inflammatory effects that help minimize irritation and erythema commonly associated with hydroquinone and tretinoin use. The combination therapy offers a synergistic approach to managing melasma by targeting pigmentation, promoting epidermal renewal, and controlling inflammation. Melanorm-F Cream should be applied once daily at bedtime to the affected areas after cleansing, avoiding contact with eyes and mucous membranes. Patients are advised to use sunscreen and limit sun exposure during treatment to prevent exacerbation of pigmentation. Adverse effects may include mild burning, redness, or peeling; prolonged use should be monitored by a healthcare professional to avoid potential corticosteroid-related side effects. This product is intended for external use only and should be used under medical supervision.
How to use Melanorm-F Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Melanorm-F Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Melanorm-F Cream is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Melanorm-F Cream

Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+2 more active ingredients
Tretinoin increases cell turnover and decreases sebum production, preventing the formation of acne lesions.
Fluocinolone Acetonide binds to glucocorticoid receptors, modulating gene expression and inhibiting the inflammatory response.
Hydroquinone inhibits the enzyme tyrosinase, reducing melanin synthesis and lightening hyperpigmented skin.
Medical applications
Melanorm-F Cream is a topical formulation containing Hydroquinone (2% w/w), Tretinoin (0.025% w/w), and Fluocinolone acetonide (0.01% w/w), indicated for the treatment of melasma and other hyperpigmentation disorders. Hydroquinone acts as a depigmenting agent by inhibiting tyrosinase, thereby reducing melanin synthesis and promoting skin lightening. Tretinoin, a retinoid, facilitates increased skin cell turnover and enhances the penetration of hydroquinone, contributing to the effective resolution of hyperpigmented lesions. Fluocinolone acetonide, a mild corticosteroid, provides anti-inflammatory effects that help minimize irritation and erythema commonly associated with hydroquinone and tretinoin use. The combination therapy offers a synergistic approach to managing melasma by targeting pigmentation, promoting epidermal renewal, and controlling inflammation. Melanorm-F Cream should be applied once daily at bedtime to the affected areas after cleansing, avoiding contact with eyes and mucous membranes. Patients are advised to use sunscreen and limit sun exposure during treatment to prevent exacerbation of pigmentation. Adverse effects may include mild burning, redness, or peeling; prolonged use should be monitored by a healthcare professional to avoid potential corticosteroid-related side effects. This product is intended for external use only and should be used under medical supervision.
How to use Melanorm-F Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Melanorm-F Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Melanorm-F Cream is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Melanorm-F Cream















