Meftal-MR Tablet
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Strip of 10 tablets • TabletPrescription requiredSchedule H
Meftal-MR Tablet
Mefenamic Acid (500mg) + Tizanidine (2mg)
₹64.50
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Mefenamic Acid 500 mg
+1 more active ingredient
How It Works
Mefenamic acid inhibits cyclooxygenase (COX) enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Tizanidine acts as an alpha-2 adrenergic agonist, inhibiting presynaptic release of excitatory neurotransmitters and reducing muscle tone.
Medicine Strength
500 mg
All Active Ingredients
Mefenamic Acid500 mg
Tizanidine2 mg
Uses & Benefits
Medical applications
Pain ReliefAnti-inflammatoryInflammationBack Pain
Meftal-MR Tablet is a combination medication containing Mefenamic Acid 500 mg and Tizanidine 2 mg, formulated for the management of moderate to severe pain associated with musculoskeletal conditions and spasticity. Mefenamic Acid, a non-steroidal anti-inflammatory drug (NSAID), exerts analgesic, anti-inflammatory, and antipyretic effects by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis involved in pain and inflammation.
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Tizanidine, a centrally acting alpha-2 adrenergic agonist, provides muscle relaxation by inhibiting motor neurons, effectively reducing muscle spasm and associated discomfort. This synergistic combination offers both pain relief and muscle relaxation, making Meftal-MR suitable for conditions such as back pain, dysmenorrhea, and musculoskeletal spasms. The extended-release formulation ensures sustained therapeutic plasma levels, enhancing patient compliance and symptom control.
Meftal-MR should be used under medical supervision, considering contraindications such as hypersensitivity to NSAIDs or tizanidine, hepatic or renal impairment, and concurrent use of interacting medications. Common adverse effects may include dizziness, drowsiness, gastrointestinal disturbances, and dry mouth. Caution is advised when operating machinery or driving. Regular monitoring and adherence to prescribed dosage are essential to minimize risks and optimize therapeutic outcomes.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Meftal-MR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Meftal-MR Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Meftal-MR Tablet should be used with caution in patients with kidney disease. Dose adjustment of Meftal-MR Tablet may be needed. Please consult your doctor.
Exercise Caution
Breastfeeding
Meftal-MR Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Kidney
Meftal-MR Tablet should be used with caution in patients with liver disease. Dose adjustment of Meftal-MR Tablet may be needed. Please consult your doctor. Use of Meftal-MR Tablet is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.
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