
Paracetamol (250mg/5ml) + Mefenamic Acid (100mg/5ml)
Active composition
+1 more active ingredient
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Mefenamic acid inhibits cyclooxygenase (COX) enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Medical applications
Mefnacid-P Syrup is a combination analgesic and antipyretic formulation containing Mefenamic Acid (100 mg/5 ml) and Paracetamol (250 mg/5 ml). It is indicated for the relief of mild to moderate pain and fever associated with various conditions such as headache, dental pain, musculoskeletal discomfort, dysmenorrhea, and febrile illnesses. Mefenamic Acid, a nonsteroidal anti-inflammatory drug (NSAID), exerts its effect by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis which mediates inflammation and pain. Paracetamol provides analgesic and antipyretic effects through central inhibition of prostaglandin synthesis, complementing the action of Mefenamic Acid. The syrup formulation facilitates ease of administration, particularly in pediatric and geriatric populations who may have difficulty swallowing tablets. Dosage should be individualized based on age, weight, and severity of symptoms, with careful adherence to recommended guidelines to minimize the risk of adverse effects such as gastrointestinal irritation, hepatotoxicity, or hypersensitivity reactions. Mefnacid-P Syrup should be used with caution in patients with a history of peptic ulcer disease, liver or kidney impairment, and should be avoided in those with known hypersensitivity to either component. Consultation with a healthcare professional is advised prior to use, especially in pregnant or lactating women.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Mefnacid-P Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Mefnacid-P Syrup is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Mefnacid-P Syrup should be used with caution in patients with kidney disease. Dose adjustment of Mefnacid-P Syrup may be needed. Please consult your doctor. Use of Mefnacid-P Syrup is not recommended in patients with severe kidney disease.
Exercise Caution
Mefnacid-P Syrup may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Mefnacid-P Syrup should be used with caution in patients with liver disease. Dose adjustment of Mefnacid-P Syrup may be needed. Please consult your doctor. However, the use of Mefnacid-P Syrup is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
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Mefenamic Acid (100mg/5ml) + Paracetamol (250mg/5ml)
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Active composition
+1 more active ingredient
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Mefenamic acid inhibits cyclooxygenase (COX) enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Medical applications
Mefnacid-P Syrup is a combination analgesic and antipyretic formulation containing Mefenamic Acid (100 mg/5 ml) and Paracetamol (250 mg/5 ml). It is indicated for the relief of mild to moderate pain and fever associated with various conditions such as headache, dental pain, musculoskeletal discomfort, dysmenorrhea, and febrile illnesses. Mefenamic Acid, a nonsteroidal anti-inflammatory drug (NSAID), exerts its effect by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis which mediates inflammation and pain. Paracetamol provides analgesic and antipyretic effects through central inhibition of prostaglandin synthesis, complementing the action of Mefenamic Acid. The syrup formulation facilitates ease of administration, particularly in pediatric and geriatric populations who may have difficulty swallowing tablets. Dosage should be individualized based on age, weight, and severity of symptoms, with careful adherence to recommended guidelines to minimize the risk of adverse effects such as gastrointestinal irritation, hepatotoxicity, or hypersensitivity reactions. Mefnacid-P Syrup should be used with caution in patients with a history of peptic ulcer disease, liver or kidney impairment, and should be avoided in those with known hypersensitivity to either component. Consultation with a healthcare professional is advised prior to use, especially in pregnant or lactating women.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Mefnacid-P Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Mefnacid-P Syrup is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Mefnacid-P Syrup should be used with caution in patients with kidney disease. Dose adjustment of Mefnacid-P Syrup may be needed. Please consult your doctor. Use of Mefnacid-P Syrup is not recommended in patients with severe kidney disease.
Exercise Caution
Mefnacid-P Syrup may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Mefnacid-P Syrup should be used with caution in patients with liver disease. Dose adjustment of Mefnacid-P Syrup may be needed. Please consult your doctor. However, the use of Mefnacid-P Syrup is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
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