
Pregabalin (50mg) + Nortriptyline (5mg) + Methylcobalamin (1500mcg)
Active composition
+2 more active ingredients
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Medical applications
Mecoverge-NT 50 Tablet SR is a combination medication containing Pregabalin 50 mg, Nortriptyline 5 mg, and Methylcobalamin 1500 mcg, formulated for sustained release to provide prolonged therapeutic effects. Pregabalin, an anticonvulsant and neuropathic pain agent, modulates calcium channels to reduce neurotransmitter release, thereby alleviating neuropathic pain and seizures. Nortriptyline, a tricyclic antidepressant, enhances noradrenaline and serotonin activity in the central nervous system, contributing to analgesic effects and mood stabilization. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair, improving nerve function and reducing neuropathy symptoms. This combination is primarily indicated for the management of neuropathic pain associated with diabetic neuropathy, postherpetic neuralgia, and other peripheral neuropathies. The sustained-release formulation ensures steady plasma concentrations, enhancing patient compliance and minimizing side effects. Mecoverge-NT 50 is contraindicated in patients with hypersensitivity to any component, severe renal impairment, or cardiac conduction abnormalities. Common adverse effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised when used concomitantly with CNS depressants or in patients with a history of cardiac arrhythmias. Mecoverge-NT 50 Tablet SR should be used under medical supervision with appropriate dosage adjustments based on clinical response and tolerability.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Mecoverge-NT 50 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Mecoverge-NT 50 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Mecoverge-NT 50 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Mecoverge-NT 50 Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Mecoverge-NT 50 Tablet SR may cause side effects which could affect your ability to drive. As Mecoverge-NT 50 Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Mecoverge-NT 50 Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mecoverge-NT 50 Tablet SR may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Mecoverge-NT 50 Tablet SR

Pregabalin (50mg) + Nortriptyline (5mg) + Methylcobalamin (1500mcg)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Medical applications
Mecoverge-NT 50 Tablet SR is a combination medication containing Pregabalin 50 mg, Nortriptyline 5 mg, and Methylcobalamin 1500 mcg, formulated for sustained release to provide prolonged therapeutic effects. Pregabalin, an anticonvulsant and neuropathic pain agent, modulates calcium channels to reduce neurotransmitter release, thereby alleviating neuropathic pain and seizures. Nortriptyline, a tricyclic antidepressant, enhances noradrenaline and serotonin activity in the central nervous system, contributing to analgesic effects and mood stabilization. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair, improving nerve function and reducing neuropathy symptoms. This combination is primarily indicated for the management of neuropathic pain associated with diabetic neuropathy, postherpetic neuralgia, and other peripheral neuropathies. The sustained-release formulation ensures steady plasma concentrations, enhancing patient compliance and minimizing side effects. Mecoverge-NT 50 is contraindicated in patients with hypersensitivity to any component, severe renal impairment, or cardiac conduction abnormalities. Common adverse effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised when used concomitantly with CNS depressants or in patients with a history of cardiac arrhythmias. Mecoverge-NT 50 Tablet SR should be used under medical supervision with appropriate dosage adjustments based on clinical response and tolerability.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Mecoverge-NT 50 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Mecoverge-NT 50 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Mecoverge-NT 50 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Mecoverge-NT 50 Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Mecoverge-NT 50 Tablet SR may cause side effects which could affect your ability to drive. As Mecoverge-NT 50 Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Mecoverge-NT 50 Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mecoverge-NT 50 Tablet SR may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Mecoverge-NT 50 Tablet SR















