
Pregabalin (75mg) + Methylcobalamin (1500mcg) + Nortriptyline (10mg)
Active composition
+2 more active ingredients
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Medical applications
Mecoryl NP 75mg/10mg/1500mcg Tablet SR is a combination pharmaceutical formulation containing Pregabalin 75mg, Nortriptyline 10mg, and Methylcobalamin 1500mcg, designed for the management of neuropathic pain and associated conditions. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channels to reduce neuronal excitability and alleviate neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission, contributing to pain relief and mood stabilization in chronic neuropathic conditions. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair, promoting improved nerve function and reducing neuropathy-related deficits. The sustained-release (SR) formulation ensures a controlled and prolonged release of active ingredients, optimizing therapeutic efficacy while minimizing dosing frequency and potential side effects. Mecoryl NP is indicated for peripheral neuropathy, diabetic neuropathy, post-herpetic neuralgia, and other neuropathic pain syndromes. It should be used under medical supervision with appropriate dose adjustments based on patient response and tolerability. Common adverse effects may include dizziness, dry mouth, sedation, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiovascular disorders, or concomitant CNS depressant use. Overall, Mecoryl NP offers a multimodal approach to neuropathic pain management, combining analgesic, antidepressant, and neurotrophic properties in a single tablet.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Mecoryl NP 75mg/10mg/1500mcg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Mecoryl NP 75mg/10mg/1500mcg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Mecoryl NP 75mg/10mg/1500mcg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Mecoryl NP 75mg/10mg/1500mcg Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Mecoryl NP 75mg/10mg/1500mcg Tablet SR may cause side effects which could affect your ability to drive. As Mecoryl NP 75mg/10mg/1500mcg Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Mecoryl NP 75mg/10mg/1500mcg Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mecoryl NP 75mg/10mg/1500mcg Tablet SR may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Mecoryl NP 75mg/10mg/1500mcg Tablet SR

Pregabalin (75mg) + Nortriptyline (10mg) + Methylcobalamin (1500mcg)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Medical applications
Mecoryl NP 75mg/10mg/1500mcg Tablet SR is a combination pharmaceutical formulation containing Pregabalin 75mg, Nortriptyline 10mg, and Methylcobalamin 1500mcg, designed for the management of neuropathic pain and associated conditions. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channels to reduce neuronal excitability and alleviate neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission, contributing to pain relief and mood stabilization in chronic neuropathic conditions. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair, promoting improved nerve function and reducing neuropathy-related deficits. The sustained-release (SR) formulation ensures a controlled and prolonged release of active ingredients, optimizing therapeutic efficacy while minimizing dosing frequency and potential side effects. Mecoryl NP is indicated for peripheral neuropathy, diabetic neuropathy, post-herpetic neuralgia, and other neuropathic pain syndromes. It should be used under medical supervision with appropriate dose adjustments based on patient response and tolerability. Common adverse effects may include dizziness, dry mouth, sedation, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiovascular disorders, or concomitant CNS depressant use. Overall, Mecoryl NP offers a multimodal approach to neuropathic pain management, combining analgesic, antidepressant, and neurotrophic properties in a single tablet.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Mecoryl NP 75mg/10mg/1500mcg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Mecoryl NP 75mg/10mg/1500mcg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Mecoryl NP 75mg/10mg/1500mcg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Mecoryl NP 75mg/10mg/1500mcg Tablet SR may be needed. Please consult your doctor.
Exercise Caution
Mecoryl NP 75mg/10mg/1500mcg Tablet SR may cause side effects which could affect your ability to drive. As Mecoryl NP 75mg/10mg/1500mcg Tablet SR may affect your alertness which may affect your ability to drive.
Consult Doctor
Mecoryl NP 75mg/10mg/1500mcg Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mecoryl NP 75mg/10mg/1500mcg Tablet SR may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Mecoryl NP 75mg/10mg/1500mcg Tablet SR















