
Fexofenadine (120mg) + Montelukast (10mg)
Active composition
+1 more active ingredient
Fexofenadine selectively antagonizes H1 histamine receptors, inhibiting the effects of histamine in allergic reactions.
Montelukast selectively antagonizes leukotriene receptors, inhibiting their effects on bronchoconstriction and inflammation.
Medical applications
Manifexo Tablet is a combination medication containing Montelukast 10 mg and Fexofenadine 120 mg, formulated for the management of allergic conditions such as allergic rhinitis and chronic urticaria. Montelukast, a leukotriene receptor antagonist, works by blocking leukotrienes, which are inflammatory mediators responsible for symptoms like bronchoconstriction, mucus production, and airway edema. Fexofenadine, a second-generation antihistamine, selectively inhibits peripheral H1 receptors, thereby reducing histamine-induced allergic symptoms including sneezing, nasal congestion, itching, and hives without causing significant sedation. The synergistic action of these two agents provides comprehensive relief from both early and late-phase allergic responses. Manifexo is indicated for patients requiring effective control of seasonal and perennial allergic rhinitis and chronic idiopathic urticaria, improving quality of life by alleviating nasal and skin symptoms. It is generally well-tolerated, with a low incidence of adverse effects such as headache, dizziness, or gastrointestinal disturbances. Caution is advised in patients with hepatic impairment and those on concomitant medications that may interact. Manifexo Tablet should be used under medical supervision, adhering to prescribed dosages to ensure optimal therapeutic outcomes and minimize potential risks.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Manifexo Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Manifexo Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
Manifexo Tablet should be used with caution in patients with kidney disease. Dose adjustment of Manifexo Tablet may be needed. Please consult your doctor. May cause excessive sleepiness in patients with end stage kidney disease.
Exercise Caution
Manifexo Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Manifexo Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Manifexo Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Manifexo Tablet

Montelukast (10mg) + Fexofenadine (120mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Fexofenadine selectively antagonizes H1 histamine receptors, inhibiting the effects of histamine in allergic reactions.
Montelukast selectively antagonizes leukotriene receptors, inhibiting their effects on bronchoconstriction and inflammation.
Medical applications
Manifexo Tablet is a combination medication containing Montelukast 10 mg and Fexofenadine 120 mg, formulated for the management of allergic conditions such as allergic rhinitis and chronic urticaria. Montelukast, a leukotriene receptor antagonist, works by blocking leukotrienes, which are inflammatory mediators responsible for symptoms like bronchoconstriction, mucus production, and airway edema. Fexofenadine, a second-generation antihistamine, selectively inhibits peripheral H1 receptors, thereby reducing histamine-induced allergic symptoms including sneezing, nasal congestion, itching, and hives without causing significant sedation. The synergistic action of these two agents provides comprehensive relief from both early and late-phase allergic responses. Manifexo is indicated for patients requiring effective control of seasonal and perennial allergic rhinitis and chronic idiopathic urticaria, improving quality of life by alleviating nasal and skin symptoms. It is generally well-tolerated, with a low incidence of adverse effects such as headache, dizziness, or gastrointestinal disturbances. Caution is advised in patients with hepatic impairment and those on concomitant medications that may interact. Manifexo Tablet should be used under medical supervision, adhering to prescribed dosages to ensure optimal therapeutic outcomes and minimize potential risks.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Manifexo Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Manifexo Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
Manifexo Tablet should be used with caution in patients with kidney disease. Dose adjustment of Manifexo Tablet may be needed. Please consult your doctor. May cause excessive sleepiness in patients with end stage kidney disease.
Exercise Caution
Manifexo Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Manifexo Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Manifexo Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Manifexo Tablet















