Macorate CR 300 Tablet
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1 units • OtherPrescription requiredSchedule H
Macorate CR 300 Tablet
Magnesium Valproate (300mg)
₹114.38
1 units • Other
A valid prescription is required for this medicine.
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Active composition
Magnesium Valproate 300 mg
How It Works
Magnesium Valproate increases GABA levels and inhibits excitatory neurotransmitter release, stabilizing neuronal activity.
Medicine Strength
300 mg
Uses & Benefits
Medical applications
Migraine
Macorate CR 300 Tablet contains Magnesium Valproate 300 mg, an anticonvulsant and mood-stabilizing agent primarily used in the management of epilepsy, bipolar disorder, and migraine prophylaxis. Magnesium Valproate acts by increasing gamma-aminobutyric acid (GABA) levels in the brain, thereby exerting an inhibitory effect on neuronal excitability and preventing seizure activity.
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The controlled-release formulation ensures a sustained therapeutic effect, improving patient compliance by reducing dosing frequency and minimizing peak-related side effects. Macorate CR 300 is indicated for the treatment of various seizure types including absence seizures, complex partial seizures, and generalized tonic-clonic seizures. Additionally, it is effective in stabilizing mood swings in bipolar disorder and reducing the frequency and severity of migraine attacks.
Common adverse effects may include gastrointestinal disturbances, dizziness, tremor, and weight gain; serious but rare side effects include hepatotoxicity and pancreatitis. Liver function tests and blood counts should be monitored periodically during therapy. Macorate CR 300 should be used cautiously in patients with hepatic impairment, mitochondrial disorders, or a history of pancreatitis.
It is contraindicated during pregnancy due to teratogenic risk. Dose adjustments may be necessary in renal or hepatic dysfunction. Always use under medical supervision.
Dosage & How to Use
How to use Macorate Tablet PR Use it as advised by your doctor or check the label for directions before use. Macorate CR 300 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is not known whether it is safe to consume alcohol with Macorate CR 300 Tablet. Please consult your doctor.
High Risk
Pregnancy
Macorate CR 300 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Driving
Macorate CR 300 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Liver
Macorate CR 300 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Breastfeeding
Macorate CR 300 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Macorate CR 300 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Macorate CR 300 Tablet may be needed. Please consult your doctor.
Regular Checkup
Customer Reviews
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