Lupitux Injection
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Vial of 20 ml • LiquidPrescription requiredSchedule H
Lupitux Injection
Cetuximab (100mg)
₹9365.00
Vial of 20 ml • Liquid
A valid prescription is required for this medicine.
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Active composition
Cetuximab 100 mg
How It Works
Cetuximab binds to EGFR, preventing ligand binding and inhibiting downstream signaling pathways that promote tumor growth.
Medicine Strength
100 mg
Uses & Benefits
Medical applications
Acne
Lupitux Injection contains Cetuximab 100 mg, a chimeric monoclonal antibody that specifically targets the epidermal growth factor receptor (EGFR). It is indicated for the treatment of patients with metastatic colorectal cancer and head and neck squamous cell carcinoma, particularly those with EGFR-expressing tumors. Cetuximab binds to the extracellular domain of EGFR, inhibiting ligand-induced receptor phosphorylation and subsequent activation of downstream signaling pathways involved in tumor cell proliferation, angiogenesis, and survival.
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Administration of Lupitux Injection is by intravenous infusion under the supervision of a qualified healthcare professional experienced in cancer therapy. Prior to initiation, patients should be tested for KRAS mutation status, as efficacy is primarily observed in those with wild-type KRAS tumors. Common adverse reactions include infusion-related reactions, dermatologic toxicities such as acneiform rash, and electrolyte imbalances, notably hypomagnesemia.
Close monitoring during and after infusion is essential to manage potential hypersensitivity reactions. Dose modifications or discontinuation may be required based on toxicity severity. Lupitux Injection should be used in combination with chemotherapy regimens as per approved guidelines. Proper patient selection and adherence to recommended dosing schedules optimize therapeutic outcomes while minimizing risks associated with cetuximab therapy.
Dosage & How to Use
How to use Lupitux Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is not known whether it is safe to consume alcohol with Lupitux Injection. Please consult your doctor.
High Risk
Driving
Lupitux Injection may cause side effects which could affect your ability to drive.
Exercise Caution
Liver
There is limited information available on the use of Lupitux Injection in patients with liver disease. Please consult your doctor.
Regular Checkup
Breastfeeding
Lupitux Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Kidney
Lupitux Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Lupitux Injection may not be needed in these patients. Please consult your doctor.
Regular Checkup
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