
Domperidone (30mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Lupisoz-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, leading to prolonged acid suppression and promoting mucosal healing. The sustained-release (SR) formulation of Lupisoz-D ensures gradual and consistent drug release, enhancing therapeutic efficacy and patient compliance. This combination is particularly beneficial in patients with acid-related disorders accompanied by delayed gastric emptying. Lupisoz-D Capsule SR should be administered as directed by a healthcare professional, typically before meals. Caution is advised in patients with known hypersensitivity to either component, hepatic impairment, or underlying cardiac conditions. Potential side effects may include headache, dry mouth, abdominal cramps, or extrapyramidal symptoms. Regular monitoring and adherence to prescribed dosage are essential to optimize treatment outcomes and minimize adverse effects.
How to use Lupisoz-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupisoz-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Lupisoz-D Capsule SR. Please consult your doctor.
High Risk
Lupisoz-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lupisoz-D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Lupisoz-D Capsule SR is recommended.
Regular Checkup
Lupisoz-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Lupisoz-D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Lupisoz-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lupisoz-D Capsule SR

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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Lupisoz-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, leading to prolonged acid suppression and promoting mucosal healing. The sustained-release (SR) formulation of Lupisoz-D ensures gradual and consistent drug release, enhancing therapeutic efficacy and patient compliance. This combination is particularly beneficial in patients with acid-related disorders accompanied by delayed gastric emptying. Lupisoz-D Capsule SR should be administered as directed by a healthcare professional, typically before meals. Caution is advised in patients with known hypersensitivity to either component, hepatic impairment, or underlying cardiac conditions. Potential side effects may include headache, dry mouth, abdominal cramps, or extrapyramidal symptoms. Regular monitoring and adherence to prescribed dosage are essential to optimize treatment outcomes and minimize adverse effects.
How to use Lupisoz-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupisoz-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Lupisoz-D Capsule SR. Please consult your doctor.
High Risk
Lupisoz-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Lupisoz-D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Lupisoz-D Capsule SR is recommended.
Regular Checkup
Lupisoz-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Lupisoz-D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Lupisoz-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lupisoz-D Capsule SR















