
Gentamicin (0.1% w/w) + Miconazole (2% w/w) + Betamethasone (0.05% w/w)
Active composition
+2 more active ingredients
Gentamicin binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death.
Miconazole inhibits the synthesis of ergosterol, compromising fungal cell membrane integrity and leading to cell death.
Betamethasone binds to glucocorticoid receptors, inhibiting the expression of pro-inflammatory genes and reducing inflammation.
Medical applications
Lupiderm GM Cream is a topical pharmaceutical formulation combining Betamethasone (0.05% w/w), Gentamicin (0.1% w/w), and Miconazole (2% w/w), designed for the management of inflammatory dermatoses complicated by secondary bacterial and fungal infections. Betamethasone, a potent corticosteroid, exerts anti-inflammatory, antipruritic, and vasoconstrictive effects, thereby reducing erythema, swelling, and itching associated with various skin conditions. Gentamicin, an aminoglycoside antibiotic, provides broad-spectrum antibacterial activity against gram-negative and some gram-positive organisms, effectively targeting secondary bacterial infections. Miconazole, an imidazole antifungal agent, inhibits ergosterol synthesis in fungal cell membranes, offering therapeutic efficacy against dermatophytes, yeasts, and other fungal pathogens. The combination cream is indicated for the treatment of corticosteroid-responsive dermatoses where bacterial and fungal infections coexist or are at risk of superinfection. Lupiderm GM Cream should be applied topically in a thin layer to the affected area, typically once or twice daily, as directed by a healthcare professional. Caution is advised in prolonged use due to potential corticosteroid-related adverse effects such as skin atrophy. It is contraindicated in viral infections, hypersensitivity to components, and should be used with care in pregnant or lactating patients. Patient adherence to prescribed duration and dosage is essential to optimize therapeutic outcomes and minimize resistance development.
How to use Lupiderm GM Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Lupiderm GM Cream is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Lupiderm GM Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Lupiderm GM Cream

Betamethasone (0.05% w/w) + Gentamicin (0.1% w/w) + Miconazole (2% w/w)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Gentamicin binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death.
Miconazole inhibits the synthesis of ergosterol, compromising fungal cell membrane integrity and leading to cell death.
Betamethasone binds to glucocorticoid receptors, inhibiting the expression of pro-inflammatory genes and reducing inflammation.
Medical applications
Lupiderm GM Cream is a topical pharmaceutical formulation combining Betamethasone (0.05% w/w), Gentamicin (0.1% w/w), and Miconazole (2% w/w), designed for the management of inflammatory dermatoses complicated by secondary bacterial and fungal infections. Betamethasone, a potent corticosteroid, exerts anti-inflammatory, antipruritic, and vasoconstrictive effects, thereby reducing erythema, swelling, and itching associated with various skin conditions. Gentamicin, an aminoglycoside antibiotic, provides broad-spectrum antibacterial activity against gram-negative and some gram-positive organisms, effectively targeting secondary bacterial infections. Miconazole, an imidazole antifungal agent, inhibits ergosterol synthesis in fungal cell membranes, offering therapeutic efficacy against dermatophytes, yeasts, and other fungal pathogens. The combination cream is indicated for the treatment of corticosteroid-responsive dermatoses where bacterial and fungal infections coexist or are at risk of superinfection. Lupiderm GM Cream should be applied topically in a thin layer to the affected area, typically once or twice daily, as directed by a healthcare professional. Caution is advised in prolonged use due to potential corticosteroid-related adverse effects such as skin atrophy. It is contraindicated in viral infections, hypersensitivity to components, and should be used with care in pregnant or lactating patients. Patient adherence to prescribed duration and dosage is essential to optimize therapeutic outcomes and minimize resistance development.
How to use Lupiderm GM Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Lupiderm GM Cream is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Lupiderm GM Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Lupiderm GM Cream















