
Rabeprazole (20mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Loreb-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the management of gastroesophageal reflux disease (GERD) and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting symptomatic relief and mucosal healing in acid-related conditions. The synergistic action of these two agents provides effective control of acid reflux symptoms, improves esophageal mucosal integrity, and facilitates gastric emptying, making Loreb-DSR suitable for patients with erosive esophagitis, non-erosive reflux disease, and functional dyspepsia. The capsule formulation ensures convenient oral administration with optimal bioavailability. Loreb-DSR should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Caution is advised in patients with known hypersensitivity to either component, underlying cardiac conditions, or hepatic impairment. Regular monitoring is recommended to assess therapeutic efficacy and detect potential adverse effects.
How to use Loreb-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loreb-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Loreb-DSR Capsule. Please consult your doctor.
High Risk
Loreb-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Loreb-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Loreb-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Loreb-DSR Capsule may be needed. Please consult your doctor. Use of Loreb-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Loreb-DSR Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Loreb-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Loreb-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Loreb-DSR Capsule

Domperidone (30mg) + Rabeprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Loreb-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the management of gastroesophageal reflux disease (GERD) and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting symptomatic relief and mucosal healing in acid-related conditions. The synergistic action of these two agents provides effective control of acid reflux symptoms, improves esophageal mucosal integrity, and facilitates gastric emptying, making Loreb-DSR suitable for patients with erosive esophagitis, non-erosive reflux disease, and functional dyspepsia. The capsule formulation ensures convenient oral administration with optimal bioavailability. Loreb-DSR should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Caution is advised in patients with known hypersensitivity to either component, underlying cardiac conditions, or hepatic impairment. Regular monitoring is recommended to assess therapeutic efficacy and detect potential adverse effects.
How to use Loreb-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loreb-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Loreb-DSR Capsule. Please consult your doctor.
High Risk
Loreb-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Loreb-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Loreb-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Loreb-DSR Capsule may be needed. Please consult your doctor. Use of Loreb-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Loreb-DSR Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Loreb-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Loreb-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Loreb-DSR Capsule















