
Domperidone (30mg) + Rabeprazole (20mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Letsrab-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30mg and Rabeprazole 20mg, designed for the effective management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief. The sustained-release (SR) formulation ensures a prolonged therapeutic effect, enhancing patient compliance by reducing dosing frequency. Letsrab-D Capsule SR is indicated for patients with acid-related disorders requiring both acid suppression and prokinetic action. It is generally well-tolerated; however, caution is advised in patients with hepatic impairment or those taking medications that may interact with domperidone or rabeprazole. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. This combination therapy should be used under medical supervision, with appropriate evaluation of contraindications and monitoring for potential side effects to optimize clinical outcomes.
How to use Letsrab-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letsrab-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Letsrab-D Capsule SR. Please consult your doctor.
High Risk
Letsrab-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Letsrab-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Letsrab-D Capsule SR may be needed. Please consult your doctor. Use of Letsrab-D Capsule SR is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Letsrab-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Letsrab-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Letsrab-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Letsrab-D Capsule SR

Domperidone (30mg) + Rabeprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Letsrab-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30mg and Rabeprazole 20mg, designed for the effective management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief. The sustained-release (SR) formulation ensures a prolonged therapeutic effect, enhancing patient compliance by reducing dosing frequency. Letsrab-D Capsule SR is indicated for patients with acid-related disorders requiring both acid suppression and prokinetic action. It is generally well-tolerated; however, caution is advised in patients with hepatic impairment or those taking medications that may interact with domperidone or rabeprazole. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. This combination therapy should be used under medical supervision, with appropriate evaluation of contraindications and monitoring for potential side effects to optimize clinical outcomes.
How to use Letsrab-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letsrab-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Letsrab-D Capsule SR. Please consult your doctor.
High Risk
Letsrab-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Letsrab-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Letsrab-D Capsule SR may be needed. Please consult your doctor. Use of Letsrab-D Capsule SR is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Letsrab-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Letsrab-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Letsrab-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Letsrab-D Capsule SR















