
Azelastine (140mcg) + Fluticasone Propionate (50mcg)
Active composition
+1 more active ingredient
Azelastine selectively antagonizes H1 receptors, reducing the effects of histamine in allergic reactions.
Fluticasone Propionate works by binding to glucocorticoid receptors, leading to the transcriptional regulation of anti-inflammatory proteins and inhibition of pro-inflammatory mediators, reducing airway inflammation.
Medical applications
Lergiset-AF Nasal Spray is a combination pharmaceutical formulation containing Fluticasone Propionate (50 mcg) and Azelastine Hydrochloride (140 mcg) per actuation, designed for the management of allergic rhinitis symptoms. Fluticasone Propionate is a potent synthetic corticosteroid with anti-inflammatory properties that effectively reduces nasal mucosal inflammation, edema, and congestion. Azelastine is a selective second-generation antihistamine that provides rapid relief by blocking histamine H1 receptors, thereby alleviating symptoms such as sneezing, nasal itching, and rhinorrhea. The dual-action mechanism of Lergiset-AF offers both immediate symptomatic relief and long-term control of nasal allergy symptoms. This nasal spray is indicated for the treatment of seasonal and perennial allergic rhinitis in adults and adolescents aged 12 years and above. It is administered intranasally, typically two sprays in each nostril twice daily, ensuring targeted delivery with minimal systemic absorption. Lergiset-AF Nasal Spray is generally well-tolerated; however, patients may experience mild adverse effects such as nasal irritation, dryness, or a bitter taste. It is contraindicated in patients with hypersensitivity to any of its components. Use during pregnancy and lactation should be under medical supervision. Lergiset-AF Nasal Spray provides an effective therapeutic option for comprehensive allergic rhinitis management.
How to use Lergiset-AF Nasal Spray Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Lergiset-AF Nasal Spray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Lergiset-AF Nasal Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Lergiset-AF Nasal Spray

Fluticasone Propionate (50mcg) + Azelastine (140mcg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Azelastine selectively antagonizes H1 receptors, reducing the effects of histamine in allergic reactions.
Fluticasone Propionate works by binding to glucocorticoid receptors, leading to the transcriptional regulation of anti-inflammatory proteins and inhibition of pro-inflammatory mediators, reducing airway inflammation.
Medical applications
Lergiset-AF Nasal Spray is a combination pharmaceutical formulation containing Fluticasone Propionate (50 mcg) and Azelastine Hydrochloride (140 mcg) per actuation, designed for the management of allergic rhinitis symptoms. Fluticasone Propionate is a potent synthetic corticosteroid with anti-inflammatory properties that effectively reduces nasal mucosal inflammation, edema, and congestion. Azelastine is a selective second-generation antihistamine that provides rapid relief by blocking histamine H1 receptors, thereby alleviating symptoms such as sneezing, nasal itching, and rhinorrhea. The dual-action mechanism of Lergiset-AF offers both immediate symptomatic relief and long-term control of nasal allergy symptoms. This nasal spray is indicated for the treatment of seasonal and perennial allergic rhinitis in adults and adolescents aged 12 years and above. It is administered intranasally, typically two sprays in each nostril twice daily, ensuring targeted delivery with minimal systemic absorption. Lergiset-AF Nasal Spray is generally well-tolerated; however, patients may experience mild adverse effects such as nasal irritation, dryness, or a bitter taste. It is contraindicated in patients with hypersensitivity to any of its components. Use during pregnancy and lactation should be under medical supervision. Lergiset-AF Nasal Spray provides an effective therapeutic option for comprehensive allergic rhinitis management.
How to use Lergiset-AF Nasal Spray Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Lergiset-AF Nasal Spray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Lergiset-AF Nasal Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Lergiset-AF Nasal Spray















