Lasinone 2mg Capsule
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Nitisinone (2mg)
Bottle of 60 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
Medical applications
Lasinone 2mg Capsule contains Nitisinone, a potent inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase, used primarily in the management of hereditary tyrosinemia type 1 (HT-1). By inhibiting this enzyme, Nitisinone reduces the production of toxic metabolites such as fumarylacetoacetate and succinylacetone, which are responsible for liver and kidney damage in affected patients.
Lasinone is indicated for long-term treatment to prevent the progression of liver dysfunction, renal tubular dysfunction, and neurological crises associated with HT-1. The recommended dosage should be individualized based on patient response and monitored through plasma succinylacetone levels and liver function tests. Adverse effects may include elevated plasma tyrosine levels, which necessitate dietary restriction of tyrosine and phenylalanine to minimize complications such as keratitis and skin lesions.
Regular ophthalmologic and biochemical monitoring is essential during therapy. Lasinone should be used with caution in patients with pre-existing liver impairment and is contraindicated in individuals with hypersensitivity to Nitisinone or any capsule components. This medication should be administered under specialist supervision, ensuring comprehensive management of HT-1 to improve patient prognosis and quality of life.
Benzoylcyclohexane-1,3-diones
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Lasinone 2mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Lasinone 2mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lasinone 2mg Capsule may be needed. Please consult your doctor.
Exercise Caution
It is not known whether Lasinone 2mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Lasinone 2mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Lasinone 2mg Capsule may be needed. Please consult your doctor.
Regular Checkup
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