Lasinone 10mg Capsule
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Bottle of 60 capsules • CapsulePrescription requiredSchedule H
Lasinone 10mg Capsule
Nitisinone (10mg)
₹50000.00
Bottle of 60 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
Nitisinone 10 mg
Medicine Strength
10 mg
Uses & Benefits
Medical applications
Skin
Lasinone 10mg Capsule contains Nitisinone, a potent inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase, used primarily in the management of hereditary tyrosinemia type 1 (HT-1). By blocking the catabolic pathway of tyrosine, Nitisinone effectively reduces the accumulation of toxic metabolites such as fumarylacetoacetate and succinylacetone, which are responsible for liver and kidney damage in affected patients.
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Lasinone is indicated for long-term treatment to prevent acute hepatic crises, renal dysfunction, and neurological complications associated with HT-1. The recommended dosage should be individualized based on patient response and monitored through biochemical markers, including plasma tyrosine and succinylacetone levels. Adverse effects may include elevated plasma tyrosine concentrations, ocular symptoms such as keratitis, and potential skin reactions; thus, regular ophthalmologic and clinical monitoring is advised.
Lasinone should be used under strict medical supervision, and dietary management restricting tyrosine and phenylalanine intake is recommended to optimize therapeutic outcomes. It is contraindicated in patients with hypersensitivity to Nitisinone or any capsule components. Caution is warranted in pregnancy and lactation due to limited safety data. Overall, Lasinone 10mg Capsule offers a targeted therapeutic approach for HT-1, improving prognosis and quality of life in affected individuals.
Dosage & How to Use
Benzoylcyclohexane-1,3-diones
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Pregnancy
Lasinone 10mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Lasinone 10mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lasinone 10mg Capsule may be needed. Please consult your doctor.
Exercise Caution
Breastfeeding
It is not known whether Lasinone 10mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Kidney
Lasinone 10mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Lasinone 10mg Capsule may be needed. Please consult your doctor.
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