
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Larsoz-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed to manage gastrointestinal disorders characterized by acid reflux and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility by enhancing the movement of the stomach and intestines, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The synergistic action of these two active ingredients makes Larsoz-DSR particularly beneficial for patients experiencing both acid reflux and impaired gastric motility. It is indicated for the treatment of GERD with associated dyspeptic symptoms and delayed gastric emptying. Larsoz-DSR should be administered as prescribed by a healthcare professional, with caution advised in patients with cardiac arrhythmias, liver impairment, or those taking medications that may interact with domperidone or esomeprazole. Regular monitoring is recommended to assess therapeutic efficacy and detect potential adverse effects. This combination therapy offers a comprehensive approach to managing complex upper gastrointestinal conditions.
How to use Larsoz-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Larsoz-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Larsoz-DSR Capsule. Please consult your doctor.
High Risk
Larsoz-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Larsoz-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Larsoz-DSR Capsule is recommended.
Regular Checkup
Larsoz-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Larsoz-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Larsoz-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Larsoz-DSR Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Larsoz-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed to manage gastrointestinal disorders characterized by acid reflux and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility by enhancing the movement of the stomach and intestines, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The synergistic action of these two active ingredients makes Larsoz-DSR particularly beneficial for patients experiencing both acid reflux and impaired gastric motility. It is indicated for the treatment of GERD with associated dyspeptic symptoms and delayed gastric emptying. Larsoz-DSR should be administered as prescribed by a healthcare professional, with caution advised in patients with cardiac arrhythmias, liver impairment, or those taking medications that may interact with domperidone or esomeprazole. Regular monitoring is recommended to assess therapeutic efficacy and detect potential adverse effects. This combination therapy offers a comprehensive approach to managing complex upper gastrointestinal conditions.
How to use Larsoz-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Larsoz-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Larsoz-DSR Capsule. Please consult your doctor.
High Risk
Larsoz-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Larsoz-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Larsoz-DSR Capsule is recommended.
Regular Checkup
Larsoz-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Larsoz-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Larsoz-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Larsoz-DSR Capsule















