
Methylcobalamin (500mcg) + Gabapentin (100mg)
Active composition
+1 more active ingredient
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Medical applications
Laregab M 100mg/500mcg Tablet is a combination medication containing Gabapentin 100mg and Methylcobalamin 500mcg, indicated primarily for the management of neuropathic pain and peripheral neuropathies. Gabapentin, an anticonvulsant, modulates neuronal excitability by inhibiting voltage-gated calcium channels, thereby reducing abnormal nerve firing and alleviating neuropathic pain symptoms. Methylcobalamin, an active form of vitamin B12, plays a crucial role in nerve regeneration and repair by promoting myelin sheath synthesis and enhancing neuronal metabolism. The synergistic effect of these two agents provides both symptomatic relief and supports nerve healing processes. Laregab M is commonly prescribed for conditions such as diabetic neuropathy, postherpetic neuralgia, and other nerve-related pain syndromes. It is generally well-tolerated, with common adverse effects including dizziness, somnolence, and gastrointestinal disturbances. Dosage should be individualized based on clinical response and tolerability, with careful monitoring in patients with renal impairment due to gabapentin’s renal excretion. This combination offers a comprehensive approach to neuropathic pain management by addressing both symptom control and underlying nerve health, thereby improving patient quality of life. It should be used under medical supervision, considering potential drug interactions and contraindications.
How to use Laregab M Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Laregab M 100mg/500mcg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Laregab M 100mg/500mcg Tablet may cause excessive drowsiness with alcohol.
High Risk
Laregab M 100mg/500mcg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
There is limited information available on the use of Laregab M 100mg/500mcg Tablet in patients with liver disease. Please consult your doctor.
Regular Checkup
Laregab M 100mg/500mcg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Laregab M 100mg/500mcg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Laregab M 100mg/500mcg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Laregab M 100mg/500mcg Tablet

Gabapentin (100mg) + Methylcobalamin (500mcg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Methylcobalamin acts as a cofactor in the synthesis of methionine from homocysteine, promoting nerve health and red blood cell formation.
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Medical applications
Laregab M 100mg/500mcg Tablet is a combination medication containing Gabapentin 100mg and Methylcobalamin 500mcg, indicated primarily for the management of neuropathic pain and peripheral neuropathies. Gabapentin, an anticonvulsant, modulates neuronal excitability by inhibiting voltage-gated calcium channels, thereby reducing abnormal nerve firing and alleviating neuropathic pain symptoms. Methylcobalamin, an active form of vitamin B12, plays a crucial role in nerve regeneration and repair by promoting myelin sheath synthesis and enhancing neuronal metabolism. The synergistic effect of these two agents provides both symptomatic relief and supports nerve healing processes. Laregab M is commonly prescribed for conditions such as diabetic neuropathy, postherpetic neuralgia, and other nerve-related pain syndromes. It is generally well-tolerated, with common adverse effects including dizziness, somnolence, and gastrointestinal disturbances. Dosage should be individualized based on clinical response and tolerability, with careful monitoring in patients with renal impairment due to gabapentin’s renal excretion. This combination offers a comprehensive approach to neuropathic pain management by addressing both symptom control and underlying nerve health, thereby improving patient quality of life. It should be used under medical supervision, considering potential drug interactions and contraindications.
How to use Laregab M Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Laregab M 100mg/500mcg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Laregab M 100mg/500mcg Tablet may cause excessive drowsiness with alcohol.
High Risk
Laregab M 100mg/500mcg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
There is limited information available on the use of Laregab M 100mg/500mcg Tablet in patients with liver disease. Please consult your doctor.
Regular Checkup
Laregab M 100mg/500mcg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Laregab M 100mg/500mcg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Laregab M 100mg/500mcg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Laregab M 100mg/500mcg Tablet















