
Gabapentin (100mg) + Amitriptyline (10mg)
Active composition
+1 more active ingredient
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Amitriptyline inhibits the reuptake of serotonin and norepinephrine, enhancing mood and providing analgesic effects.
Medical applications
Laregab AT LS 100mg/10mg Tablet is a combination medication containing Gabapentin 100mg and Amitriptyline 10mg, primarily indicated for the management of neuropathic pain and certain types of chronic pain disorders. Gabapentin, an anticonvulsant, modulates neuronal excitability by binding to voltage-gated calcium channels in the central nervous system, thereby reducing neuropathic pain signals. Amitriptyline, a tricyclic antidepressant, enhances the inhibitory effects of serotonin and norepinephrine by blocking their reuptake, contributing to analgesic and mood-stabilizing properties. The synergistic effect of these two agents provides effective pain relief while potentially improving sleep disturbances associated with chronic pain conditions. Laregab AT LS is typically prescribed when monotherapy has proven insufficient or when a multimodal approach is warranted. It is essential to adhere to the prescribed dosage and consult a healthcare professional before initiating therapy, as both components have specific contraindications and potential side effects, including dizziness, drowsiness, dry mouth, and gastrointestinal discomfort. Caution is advised in patients with a history of cardiac disorders, glaucoma, or renal impairment. Regular monitoring and dose adjustments may be necessary to optimize therapeutic outcomes and minimize adverse effects. This combination should not be abruptly discontinued to avoid withdrawal symptoms.
How to use Laregab AT LS Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Laregab AT LS 100mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Laregab AT LS 100mg/10mg Tablet.
High Risk
Laregab AT LS 100mg/10mg Tablet may cause side effects which could affect your ability to drive. Laregab AT LS 100mg/10mg Tablet may impair your alertness which may affect your ability to drive.
Exercise Caution
Laregab AT LS 100mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Laregab AT LS 100mg/10mg Tablet may be needed. Please consult your doctor. Use of Laregab AT LS 100mg/10mg Tablet is not recommended in patients with severe liver disease.
Regular Checkup
Laregab AT LS 100mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Laregab AT LS 100mg/10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Laregab AT LS 100mg/10mg Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Laregab AT LS 100mg/10mg Tablet

Gabapentin (100mg) + Amitriptyline (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Amitriptyline inhibits the reuptake of serotonin and norepinephrine, enhancing mood and providing analgesic effects.
Medical applications
Laregab AT LS 100mg/10mg Tablet is a combination medication containing Gabapentin 100mg and Amitriptyline 10mg, primarily indicated for the management of neuropathic pain and certain types of chronic pain disorders. Gabapentin, an anticonvulsant, modulates neuronal excitability by binding to voltage-gated calcium channels in the central nervous system, thereby reducing neuropathic pain signals. Amitriptyline, a tricyclic antidepressant, enhances the inhibitory effects of serotonin and norepinephrine by blocking their reuptake, contributing to analgesic and mood-stabilizing properties. The synergistic effect of these two agents provides effective pain relief while potentially improving sleep disturbances associated with chronic pain conditions. Laregab AT LS is typically prescribed when monotherapy has proven insufficient or when a multimodal approach is warranted. It is essential to adhere to the prescribed dosage and consult a healthcare professional before initiating therapy, as both components have specific contraindications and potential side effects, including dizziness, drowsiness, dry mouth, and gastrointestinal discomfort. Caution is advised in patients with a history of cardiac disorders, glaucoma, or renal impairment. Regular monitoring and dose adjustments may be necessary to optimize therapeutic outcomes and minimize adverse effects. This combination should not be abruptly discontinued to avoid withdrawal symptoms.
How to use Laregab AT LS Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Laregab AT LS 100mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Laregab AT LS 100mg/10mg Tablet.
High Risk
Laregab AT LS 100mg/10mg Tablet may cause side effects which could affect your ability to drive. Laregab AT LS 100mg/10mg Tablet may impair your alertness which may affect your ability to drive.
Exercise Caution
Laregab AT LS 100mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Laregab AT LS 100mg/10mg Tablet may be needed. Please consult your doctor. Use of Laregab AT LS 100mg/10mg Tablet is not recommended in patients with severe liver disease.
Regular Checkup
Laregab AT LS 100mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Laregab AT LS 100mg/10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Laregab AT LS 100mg/10mg Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Laregab AT LS 100mg/10mg Tablet















