Lacotide 100mg Tablet contains lacosamide, an anticonvulsant indicated for the treatment of partial-onset seizures in patients with epilepsy. Lacosamide acts by selectively enhancing slow inactivation of voltage-gated sodium channels, stabilizing hyperexcitable neuronal membranes and inhibiting repetitive neuronal firing. This mechanism helps reduce the frequency and severity of seizures. Lacotide is typically prescribed as adjunctive therapy for adults and pediatric patients aged four years and older who have refractory partial-onset seizures. The recommended initial dose is 50 mg twice daily, with gradual titration based on clinical response and tolerability, up to a maximum dose of 400 mg per day. Lacotide is well absorbed orally, with peak plasma concentrations achieved within 1 to 4 hours and a half-life of approximately 13 hours, allowing for twice-daily dosing. Common adverse effects include dizziness, headache, nausea, and diplopia, which are generally mild to moderate in intensity. Caution is advised in patients with cardiac conduction abnormalities, as lacosamide may prolong PR interval. Regular monitoring and dose adjustments may be necessary in patients with renal or hepatic impairment. Lacotide should be used under medical supervision with consideration of potential drug interactions.

Dosage & How to Use