Lacne Gel
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Adapalene (0.1% w/w) + Clindamycin (1% w/w)
Tube of 15 gm • Gel
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Clindamycin binds to the 50S ribosomal subunit, inhibiting protein synthesis in bacteria.
Medical applications
Lacne Gel is a topical dermatological formulation containing Adapalene 0.1% w/w and Clindamycin 1% w/w, indicated for the treatment of acne vulgaris. Adapalene, a third-generation synthetic retinoid, modulates cellular differentiation and keratinization, thereby preventing the formation of microcomedones and promoting the resolution of existing comedones and inflammatory lesions.
Clindamycin, a lincosamide antibiotic, exerts bacteriostatic effects against Propionibacterium acnes by inhibiting bacterial protein synthesis, reducing inflammation and bacterial colonization within pilosebaceous units. The combination of these active ingredients provides a dual mechanism of action targeting both the inflammatory and non-inflammatory components of acne. Lacne Gel is applied once daily to affected areas after cleansing, avoiding contact with eyes, lips, and mucous membranes.
Common adverse effects may include mild to moderate local irritation such as erythema, dryness, peeling, and burning sensation, which typically diminish with continued use. Patients are advised to use sunscreen and avoid excessive sun exposure during treatment due to increased photosensitivity. Lacne Gel is contraindicated in individuals with hypersensitivity to adapalene, clindamycin, or any formulation excipients.
It is recommended to consult a healthcare professional prior to initiation, especially in pregnant or breastfeeding women.
How to use Lacne Gel This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
No interaction found/established
High Risk
Lacne Gel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Lacne Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
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