Kyzific 40mg Tablet
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Bottle of 60 tablets • TabletPrescription requiredSchedule H
Kyzific 40mg Tablet
Asciminib (40mg)
₹235000.00
Bottle of 60 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Asciminib 40 mg
Medicine Strength
40 mg
Uses & Benefits
Medical applications
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Kyzific 40mg Tablet contains Asciminib, a targeted therapy indicated for the treatment of adult patients with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase who have been previously treated with two or more tyrosine kinase inhibitors (TKIs). Asciminib functions as a selective allosteric inhibitor of the BCR-ABL1 fusion protein, which plays a critical role in the pathogenesis of CML by promoting uncontrolled cell proliferation.
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By binding to the myristoyl pocket of the BCR-ABL1 protein, Asciminib inhibits its kinase activity, thereby reducing leukemic cell growth and proliferation. Kyzific is administered orally, with a recommended dosage tailored according to the patient’s clinical response and tolerance. Common adverse effects may include fatigue, nausea, musculoskeletal pain, and elevated liver enzymes, necessitating regular monitoring of hepatic function and blood counts during therapy.
Kyzific should be used under strict medical supervision, with dose adjustments considered in cases of toxicity or drug interactions. It represents a valuable therapeutic option for patients with resistant or intolerant Ph+ CML, offering improved disease control and potential for durable remission. Physicians should evaluate the risk-benefit profile prior to initiation and counsel patients regarding adherence and potential side effects.
Dosage & How to Use
How to use Kyzific Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kyzific 40mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is not known whether it is safe to consume alcohol with Kyzific 40mg Tablet. Please consult your doctor.
High Risk
Pregnancy
Kyzific 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
It is not known whether Kyzific 40mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
Liver
Kyzific 40mg Tablet is safe to use in patients with liver disease. No dose adjustment of Kyzific 40mg Tablet is recommended.
Regular Checkup
Breastfeeding
Kyzific 40mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Kidney
Kyzific 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Kyzific 40mg Tablet is recommended.
Regular Checkup
Customer Reviews
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