Koolact-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the management of gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and discomfort associated with delayed gastric emptying. Rabeprazole, a proton pump inhibitor, suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related disorders such as gastroesophageal reflux disease (GERD), peptic ulcers, and erosive esophagitis. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, enhancing patient compliance and symptom control. Koolact-D Capsule SR is indicated for patients experiencing symptomatic gastroesophageal reflux, functional dyspepsia, and conditions requiring both acid suppression and prokinetic action. The combination improves esophageal clearance and reduces acid exposure, promoting mucosal healing and symptom resolution. It should be administered as prescribed by a healthcare professional, with consideration of contraindications such as hypersensitivity to components and caution in patients with cardiac arrhythmias or hepatic impairment. Adverse effects may include headache, dry mouth, abdominal cramps, or diarrhea. Regular monitoring and adherence to dosage instructions are essential for optimal therapeutic outcomes.

Dosage & How to Use