
Diphenhydramine (25mg) + Caffeine (30mg) + Phenylephrine (10mg) + Paracetamol (500mg)
Active composition
+3 more active ingredients
Diphenhydramine works by selectively antagonizing H1 histamine receptors, thereby inhibiting the effects of histamine during allergic reactions.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Medical applications
Kofwise-CP Tablet is a combination pharmaceutical formulation containing Caffeine (30mg), Diphenhydramine (25mg), Paracetamol (500mg), and Phenylephrine (10mg), designed for the symptomatic relief of common cold, flu, and associated conditions. Paracetamol acts as an analgesic and antipyretic, effectively reducing fever and alleviating mild to moderate pain. Diphenhydramine, a first-generation antihistamine, provides relief from allergic symptoms such as sneezing, runny nose, and watery eyes, while also exerting sedative effects that may aid in improving sleep quality during illness. Phenylephrine serves as a selective alpha-1 adrenergic receptor agonist, promoting vasoconstriction and thereby reducing nasal congestion. Caffeine acts as a central nervous system stimulant, counteracting the sedative effects of diphenhydramine and enhancing alertness. This combination is intended for short-term use to manage multiple symptoms concurrently, improving patient comfort and functionality. Kofwise-CP should be used with caution in individuals with hypertension, cardiovascular disorders, or hypersensitivity to any component. It is contraindicated in patients with severe liver impairment or glaucoma. Dosage should be strictly adhered to as per medical advice to avoid potential adverse effects such as nervousness, insomnia, or gastrointestinal disturbances.
How to use Kofwise-CP Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kofwise-CP Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Kofwise-CP Tablet.
High Risk
Kofwise-CP Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Kofwise-CP Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Kofwise-CP Tablet should be used with caution in patients with liver disease. Dose adjustment of Kofwise-CP Tablet may be needed. Please consult your doctor.
Regular Checkup
Kofwise-CP Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Kofwise-CP Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Kofwise-CP Tablet may be needed. Please consult your doctor. Regular monitoring of blood pressure is advised for dose adjustment.
Regular Checkup
0 reviews for Kofwise-CP Tablet

Caffeine (30mg) + Diphenhydramine (25mg) + Paracetamol (500mg) + Phenylephrine (10mg)
Cheaper alternative availability
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Active composition
+3 more active ingredients
Diphenhydramine works by selectively antagonizing H1 histamine receptors, thereby inhibiting the effects of histamine during allergic reactions.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Medical applications
Kofwise-CP Tablet is a combination pharmaceutical formulation containing Caffeine (30mg), Diphenhydramine (25mg), Paracetamol (500mg), and Phenylephrine (10mg), designed for the symptomatic relief of common cold, flu, and associated conditions. Paracetamol acts as an analgesic and antipyretic, effectively reducing fever and alleviating mild to moderate pain. Diphenhydramine, a first-generation antihistamine, provides relief from allergic symptoms such as sneezing, runny nose, and watery eyes, while also exerting sedative effects that may aid in improving sleep quality during illness. Phenylephrine serves as a selective alpha-1 adrenergic receptor agonist, promoting vasoconstriction and thereby reducing nasal congestion. Caffeine acts as a central nervous system stimulant, counteracting the sedative effects of diphenhydramine and enhancing alertness. This combination is intended for short-term use to manage multiple symptoms concurrently, improving patient comfort and functionality. Kofwise-CP should be used with caution in individuals with hypertension, cardiovascular disorders, or hypersensitivity to any component. It is contraindicated in patients with severe liver impairment or glaucoma. Dosage should be strictly adhered to as per medical advice to avoid potential adverse effects such as nervousness, insomnia, or gastrointestinal disturbances.
How to use Kofwise-CP Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kofwise-CP Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Kofwise-CP Tablet.
High Risk
Kofwise-CP Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Kofwise-CP Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Kofwise-CP Tablet should be used with caution in patients with liver disease. Dose adjustment of Kofwise-CP Tablet may be needed. Please consult your doctor.
Regular Checkup
Kofwise-CP Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Kofwise-CP Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Kofwise-CP Tablet may be needed. Please consult your doctor. Regular monitoring of blood pressure is advised for dose adjustment.
Regular Checkup
0 reviews for Kofwise-CP Tablet















