
Dextromethorphan Hydrobromide (10mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Phenylephrine (5mg/5ml)
Active composition
+2 more active ingredients
Dextromethorphan acts on the cough center in the brain, reducing the urge to cough.
Chlorpheniramine Maleate antagonizes H1 receptors, preventing the action of histamine and reducing allergy symptoms.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Medical applications
Kofsum-DX Syrup is a combination pharmaceutical formulation containing Phenylephrine (5mg/5ml), Chlorpheniramine Maleate (2mg/5ml), and Dextromethorphan Hydrobromide (10mg/5ml). This syrup is indicated for the symptomatic relief of upper respiratory tract conditions characterized by nasal congestion, allergic rhinitis, and cough. Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, providing effective nasal decongestion by vasoconstriction of the nasal mucosa. Chlorpheniramine Maleate is a first-generation antihistamine that alleviates allergic symptoms such as sneezing, runny nose, and itching by competitively inhibiting histamine H1 receptors. Dextromethorphan Hydrobromide serves as a centrally acting antitussive agent that suppresses the cough reflex by acting on the medullary cough center without causing significant respiratory depression. Kofsum-DX Syrup is suitable for adults and children above the recommended age and should be used according to the prescribed dosage to minimize adverse effects such as drowsiness, dizziness, or gastrointestinal disturbances. Caution is advised in patients with hypertension, glaucoma, or concurrent use of monoamine oxidase inhibitors. This combination therapy offers a comprehensive approach to managing cold and allergy symptoms, enhancing patient comfort and facilitating recovery.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Kofsum-DX Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Kofsum-DX Syrup is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Kofsum-DX Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kofsum-DX Syrup may not be needed in these patients. Please consult your doctor.
Exercise Caution
Kofsum-DX Syrup may cause side effects which could affect your ability to drive.
Consult Doctor
Kofsum-DX Syrup is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Kofsum-DX Syrup

Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Dextromethorphan acts on the cough center in the brain, reducing the urge to cough.
Chlorpheniramine Maleate antagonizes H1 receptors, preventing the action of histamine and reducing allergy symptoms.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Medical applications
Kofsum-DX Syrup is a combination pharmaceutical formulation containing Phenylephrine (5mg/5ml), Chlorpheniramine Maleate (2mg/5ml), and Dextromethorphan Hydrobromide (10mg/5ml). This syrup is indicated for the symptomatic relief of upper respiratory tract conditions characterized by nasal congestion, allergic rhinitis, and cough. Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, providing effective nasal decongestion by vasoconstriction of the nasal mucosa. Chlorpheniramine Maleate is a first-generation antihistamine that alleviates allergic symptoms such as sneezing, runny nose, and itching by competitively inhibiting histamine H1 receptors. Dextromethorphan Hydrobromide serves as a centrally acting antitussive agent that suppresses the cough reflex by acting on the medullary cough center without causing significant respiratory depression. Kofsum-DX Syrup is suitable for adults and children above the recommended age and should be used according to the prescribed dosage to minimize adverse effects such as drowsiness, dizziness, or gastrointestinal disturbances. Caution is advised in patients with hypertension, glaucoma, or concurrent use of monoamine oxidase inhibitors. This combination therapy offers a comprehensive approach to managing cold and allergy symptoms, enhancing patient comfort and facilitating recovery.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Kofsum-DX Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Kofsum-DX Syrup is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Kofsum-DX Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kofsum-DX Syrup may not be needed in these patients. Please consult your doctor.
Exercise Caution
Kofsum-DX Syrup may cause side effects which could affect your ability to drive.
Consult Doctor
Kofsum-DX Syrup is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Kofsum-DX Syrup















