
Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml) + Phenylephrine (5mg/5ml)
Active composition
+2 more active ingredients
Chlorpheniramine Maleate antagonizes H1 receptors, preventing the action of histamine and reducing allergy symptoms.
Dextromethorphan acts on the cough center in the brain, reducing the urge to cough.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Medical applications
Kofsin-DMR Syrup is a combination medication formulated to provide symptomatic relief from cough and nasal congestion associated with upper respiratory tract infections, allergic rhinitis, and the common cold. Each 5 ml of this syrup contains Phenylephrine (5 mg), a selective alpha-1 adrenergic receptor agonist that acts as a decongestant by constricting dilated blood vessels in the nasal mucosa, thereby reducing swelling and nasal congestion. It also contains Chlorpheniramine Maleate (2 mg), a first-generation antihistamine that competitively inhibits histamine H1 receptors, alleviating allergic symptoms such as sneezing, runny nose, and watery eyes. Additionally, Dextromethorphan Hydrobromide (10 mg) is included as a centrally acting antitussive agent that suppresses the cough reflex by acting on the medullary cough center without causing sedation or respiratory depression. Kofsin-DMR Syrup is indicated for temporary relief of cough, nasal congestion, and allergy-related symptoms. It should be used with caution in patients with hypertension, cardiovascular disease, glaucoma, or hyperthyroidism. The syrup is contraindicated in individuals hypersensitive to any of its components and should not be administered concomitantly with monoamine oxidase inhibitors. Dosage should be adhered to as per medical advice to minimize the risk of adverse effects.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Kofsin-DMR Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Kofsin-DMR Syrup is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Kofsin-DMR Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kofsin-DMR Syrup may not be needed in these patients. Please consult your doctor.
Exercise Caution
Kofsin-DMR Syrup may cause side effects which could affect your ability to drive.
Consult Doctor
Kofsin-DMR Syrup is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Kofsin-DMR Syrup

Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Chlorpheniramine Maleate antagonizes H1 receptors, preventing the action of histamine and reducing allergy symptoms.
Dextromethorphan acts on the cough center in the brain, reducing the urge to cough.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Medical applications
Kofsin-DMR Syrup is a combination medication formulated to provide symptomatic relief from cough and nasal congestion associated with upper respiratory tract infections, allergic rhinitis, and the common cold. Each 5 ml of this syrup contains Phenylephrine (5 mg), a selective alpha-1 adrenergic receptor agonist that acts as a decongestant by constricting dilated blood vessels in the nasal mucosa, thereby reducing swelling and nasal congestion. It also contains Chlorpheniramine Maleate (2 mg), a first-generation antihistamine that competitively inhibits histamine H1 receptors, alleviating allergic symptoms such as sneezing, runny nose, and watery eyes. Additionally, Dextromethorphan Hydrobromide (10 mg) is included as a centrally acting antitussive agent that suppresses the cough reflex by acting on the medullary cough center without causing sedation or respiratory depression. Kofsin-DMR Syrup is indicated for temporary relief of cough, nasal congestion, and allergy-related symptoms. It should be used with caution in patients with hypertension, cardiovascular disease, glaucoma, or hyperthyroidism. The syrup is contraindicated in individuals hypersensitive to any of its components and should not be administered concomitantly with monoamine oxidase inhibitors. Dosage should be adhered to as per medical advice to minimize the risk of adverse effects.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Kofsin-DMR Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Kofsin-DMR Syrup is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Kofsin-DMR Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kofsin-DMR Syrup may not be needed in these patients. Please consult your doctor.
Exercise Caution
Kofsin-DMR Syrup may cause side effects which could affect your ability to drive.
Consult Doctor
Kofsin-DMR Syrup is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Kofsin-DMR Syrup















