
Dextromethorphan Hydrobromide (10mg/5ml) + Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml)
Active composition
+2 more active ingredients
Dextromethorphan acts on the cough center in the brain, reducing the urge to cough.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Chlorpheniramine Maleate antagonizes H1 receptors, preventing the action of histamine and reducing allergy symptoms.
Medical applications
Kofegril-DX Syrup is a combination pharmaceutical formulation containing Phenylephrine (5mg/5ml), Chlorpheniramine Maleate (2mg/5ml), and Dextromethorphan Hydrobromide (10mg/5ml). It is indicated for the symptomatic relief of cough and nasal congestion associated with common cold, allergic rhinitis, and upper respiratory tract infections. Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, providing effective vasoconstriction of nasal mucosa blood vessels, thereby reducing nasal congestion. Chlorpheniramine Maleate is a first-generation antihistamine that competitively inhibits histamine H1 receptors, alleviating allergic symptoms such as sneezing, runny nose, and itching. Dextromethorphan Hydrobromide functions as a centrally acting antitussive agent, suppressing the cough reflex by acting on the medullary cough center without causing significant sedation or respiratory depression. The syrup formulation ensures ease of administration and rapid onset of action. Kofegril-DX Syrup should be used with caution in patients with hypertension, glaucoma, or hyperthyroidism, and is contraindicated in those with known hypersensitivity to any of its components. Dosage adjustments may be necessary in pediatric and elderly populations. Consultation with a healthcare professional is recommended before use to ensure safety and efficacy.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Kofegril-DX Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Kofegril-DX Syrup is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Kofegril-DX Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kofegril-DX Syrup may not be needed in these patients. Please consult your doctor.
Exercise Caution
Kofegril-DX Syrup may cause side effects which could affect your ability to drive.
Consult Doctor
Kofegril-DX Syrup is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Kofegril-DX Syrup

Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Dextromethorphan acts on the cough center in the brain, reducing the urge to cough.
Phenylephrine activates alpha-adrenergic receptors, leading to vasoconstriction and reduced blood flow to nasal mucosa, thereby decreasing swelling and congestion.
Chlorpheniramine Maleate antagonizes H1 receptors, preventing the action of histamine and reducing allergy symptoms.
Medical applications
Kofegril-DX Syrup is a combination pharmaceutical formulation containing Phenylephrine (5mg/5ml), Chlorpheniramine Maleate (2mg/5ml), and Dextromethorphan Hydrobromide (10mg/5ml). It is indicated for the symptomatic relief of cough and nasal congestion associated with common cold, allergic rhinitis, and upper respiratory tract infections. Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, providing effective vasoconstriction of nasal mucosa blood vessels, thereby reducing nasal congestion. Chlorpheniramine Maleate is a first-generation antihistamine that competitively inhibits histamine H1 receptors, alleviating allergic symptoms such as sneezing, runny nose, and itching. Dextromethorphan Hydrobromide functions as a centrally acting antitussive agent, suppressing the cough reflex by acting on the medullary cough center without causing significant sedation or respiratory depression. The syrup formulation ensures ease of administration and rapid onset of action. Kofegril-DX Syrup should be used with caution in patients with hypertension, glaucoma, or hyperthyroidism, and is contraindicated in those with known hypersensitivity to any of its components. Dosage adjustments may be necessary in pediatric and elderly populations. Consultation with a healthcare professional is recommended before use to ensure safety and efficacy.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Kofegril-DX Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Kofegril-DX Syrup is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Kofegril-DX Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kofegril-DX Syrup may not be needed in these patients. Please consult your doctor.
Exercise Caution
Kofegril-DX Syrup may cause side effects which could affect your ability to drive.
Consult Doctor
Kofegril-DX Syrup is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
0 reviews for Kofegril-DX Syrup















