Klinface-A Gel
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Adapalene (0.1% w/w) + Clindamycin (1% w/w)
Tube of 15 gm • Gel
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Active composition
+1 more active ingredient
Clindamycin binds to the 50S ribosomal subunit, inhibiting protein synthesis in bacteria.
Medical applications
Klinface-A Gel is a topical dermatological formulation containing Adapalene 0.1% w/w and Clindamycin 1% w/w, indicated for the treatment of acne vulgaris. Adapalene, a third-generation synthetic retinoid, modulates cellular differentiation and keratinization, thereby preventing the formation of microcomedones and promoting the normalization of follicular epithelial desquamation.
Clindamycin, a lincosamide antibiotic, exhibits bacteriostatic activity against Propionibacterium acnes by inhibiting bacterial protein synthesis, reducing inflammation and bacterial colonization within the pilosebaceous unit. The combination of these active ingredients addresses both the inflammatory and comedonal components of acne, enhancing therapeutic efficacy compared to monotherapy.
Klinface-A Gel is applied once daily to the affected areas after cleansing, typically in the evening. Common adverse effects may include mild erythema, dryness, peeling, and transient burning or stinging sensations at the application site, which usually subside with continued use. Patients are advised to avoid excessive sun exposure and use sunscreen during treatment. This product is contraindicated in individuals with hypersensitivity to adapalene, clindamycin, or any formulation excipients.
Clinical use should be guided by a healthcare professional to optimize outcomes and minimize adverse reactions.
How to use Klinface-A Gel This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
No interaction found/established
High Risk
Klinface-A Gel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Klinface-A Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
No interaction found/established
Regular Checkup
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