
Domperidone (10mg) + Pantoprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Medical applications
Kepran-D Tablet is a combination medication containing Domperidone 10 mg and Pantoprazole 40 mg, formulated to manage gastrointestinal disorders characterized by acid reflux and delayed gastric emptying. Domperidone, a dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the movement of the stomach and intestines, thereby facilitating gastric emptying and alleviating symptoms such as nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing relief from acid-related conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. The synergistic action of these two agents addresses both the motility and acid secretion components of upper gastrointestinal disorders, improving patient outcomes. Kepran-D is indicated for the treatment of symptomatic GERD, dyspepsia, and other acid-peptic diseases accompanied by delayed gastric emptying. It is generally well tolerated; however, patients should use it under medical supervision, especially those with cardiac conditions or electrolyte imbalances, due to potential side effects such as QT prolongation associated with Domperidone. Dosage and duration should be individualized based on clinical response and physician guidance.
How to use Kepran-D Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kepran-D Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Kepran-D Tablet. Please consult your doctor.
High Risk
Kepran-D Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Kepran-D Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Kepran-D Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Kepran-D Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
Kepran-D Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Kepran-D Tablet should be used with caution in patients with kidney disease. Dose adjustment of Kepran-D Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Kepran-D Tablet

Domperidone (10mg) + Pantoprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Medical applications
Kepran-D Tablet is a combination medication containing Domperidone 10 mg and Pantoprazole 40 mg, formulated to manage gastrointestinal disorders characterized by acid reflux and delayed gastric emptying. Domperidone, a dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the movement of the stomach and intestines, thereby facilitating gastric emptying and alleviating symptoms such as nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing relief from acid-related conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. The synergistic action of these two agents addresses both the motility and acid secretion components of upper gastrointestinal disorders, improving patient outcomes. Kepran-D is indicated for the treatment of symptomatic GERD, dyspepsia, and other acid-peptic diseases accompanied by delayed gastric emptying. It is generally well tolerated; however, patients should use it under medical supervision, especially those with cardiac conditions or electrolyte imbalances, due to potential side effects such as QT prolongation associated with Domperidone. Dosage and duration should be individualized based on clinical response and physician guidance.
How to use Kepran-D Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kepran-D Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Kepran-D Tablet. Please consult your doctor.
High Risk
Kepran-D Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Kepran-D Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Kepran-D Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Kepran-D Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
Kepran-D Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Kepran-D Tablet should be used with caution in patients with kidney disease. Dose adjustment of Kepran-D Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Kepran-D Tablet















