
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Jupicid DSR 30mg/40mg Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, designed to manage gastrointestinal disorders characterized by acid reflux and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the movement of the stomach and intestines, thereby facilitating gastric emptying and reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, effectively reducing gastric acidity and promoting mucosal healing in conditions like gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcer disease. The combined action of these agents provides symptomatic relief from heartburn, acid regurgitation, and dyspepsia while improving gastric motility. Jupicid DSR is indicated for the treatment of GERD with associated motility disorders and is typically administered orally once daily before meals. Caution is advised in patients with known hypersensitivity to either component, significant hepatic or renal impairment, and those on medications that may interact with domperidone or esomeprazole. Consultation with a healthcare professional is essential prior to initiation to ensure appropriate use and monitoring.
How to use Jupicid D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jupicid DSR 30mg/40mg Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Jupicid DSR 30mg/40mg Capsule. Please consult your doctor.
High Risk
Jupicid DSR 30mg/40mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Jupicid DSR 30mg/40mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Jupicid DSR 30mg/40mg Capsule is safe to use in patients with liver disease. No dose adjustment of Jupicid DSR 30mg/40mg Capsule is recommended.
Regular Checkup
Jupicid DSR 30mg/40mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Jupicid DSR 30mg/40mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Jupicid DSR 30mg/40mg Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Jupicid DSR 30mg/40mg Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Jupicid DSR 30mg/40mg Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, designed to manage gastrointestinal disorders characterized by acid reflux and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the movement of the stomach and intestines, thereby facilitating gastric emptying and reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, effectively reducing gastric acidity and promoting mucosal healing in conditions like gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcer disease. The combined action of these agents provides symptomatic relief from heartburn, acid regurgitation, and dyspepsia while improving gastric motility. Jupicid DSR is indicated for the treatment of GERD with associated motility disorders and is typically administered orally once daily before meals. Caution is advised in patients with known hypersensitivity to either component, significant hepatic or renal impairment, and those on medications that may interact with domperidone or esomeprazole. Consultation with a healthcare professional is essential prior to initiation to ensure appropriate use and monitoring.
How to use Jupicid D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jupicid DSR 30mg/40mg Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Jupicid DSR 30mg/40mg Capsule. Please consult your doctor.
High Risk
Jupicid DSR 30mg/40mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Jupicid DSR 30mg/40mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Jupicid DSR 30mg/40mg Capsule is safe to use in patients with liver disease. No dose adjustment of Jupicid DSR 30mg/40mg Capsule is recommended.
Regular Checkup
Jupicid DSR 30mg/40mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Jupicid DSR 30mg/40mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Jupicid DSR 30mg/40mg Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Jupicid DSR 30mg/40mg Capsule















