Jakavi 5mg Tablet
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Strip of 10 tablets • TabletPrescription requiredSchedule H
Jakavi 5mg Tablet
Ruxolitinib (5mg)
₹23615.00
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Ruxolitinib 5 mg
How It Works
Ruxolitinib inhibits Janus kinases (JAK1 and JAK2), reducing signaling pathways that promote cell growth and survival in myeloproliferative disorders.
Medicine Strength
5 mg
Uses & Benefits
Medical applications
Headache
Jakavi 5mg Tablet contains Ruxolitinib, a selective Janus kinase (JAK) 1 and 2 inhibitor used primarily in the treatment of myeloproliferative disorders. It is indicated for patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis, to reduce splenomegaly and alleviate disease-related symptoms.
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Jakavi is also approved for the treatment of polycythemia vera in patients who have had an inadequate response to or are intolerant of hydroxyurea. The mechanism of action involves the inhibition of dysregulated JAK-STAT signaling pathways, which play a critical role in the pathogenesis of these hematologic conditions. Jakavi 5mg tablets are administered orally, with dosage individualized based on patient response and tolerability.
Common adverse effects include anemia, thrombocytopenia, bruising, dizziness, and headache, necessitating regular monitoring of blood counts during therapy. Caution is advised in patients with hepatic or renal impairment. Jakavi should be prescribed and managed by healthcare professionals experienced in the treatment of hematologic malignancies, ensuring appropriate patient selection and monitoring to optimize therapeutic outcomes while minimizing risks.
Dosage & How to Use
Pyrrolo[2,3-d]pyrimidines Derivative
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Jakavi 5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Jakavi 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Jakavi 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Jakavi 5mg Tablet may be needed. Please consult your doctor. Use of Jakavi 5mg Tablet is not advised in patients with moderate to severe kidney disease.
Exercise Caution
Breastfeeding
Jakavi 5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Kidney
Jakavi 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Jakavi 5mg Tablet may be needed. Please consult your doctor.
Regular Checkup
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