
Domperidone (30mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Izumep Capsule SR is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, designed for the management of gastrointestinal disorders characterized by acid reflux, dyspepsia, and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, enhancing patient compliance and symptom control. Izumep Capsule SR is indicated in patients requiring both acid suppression and prokinetic therapy to improve upper gastrointestinal motility and reduce acid exposure. It should be administered as prescribed by a healthcare professional, with caution advised in patients with known hypersensitivity to its components, significant hepatic impairment, or underlying cardiac conditions due to the potential risk of QT interval prolongation associated with Domperidone. Regular monitoring and adherence to recommended dosages are essential to maximize efficacy and minimize adverse effects.
How to use Izumep Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Izumep Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Izumep Capsule SR. Please consult your doctor.
High Risk
Izumep Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Izumep Capsule SR is safe to use in patients with liver disease. No dose adjustment of Izumep Capsule SR is recommended.
Regular Checkup
Izumep Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Izumep Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Izumep Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Izumep Capsule SR

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Izumep Capsule SR is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, designed for the management of gastrointestinal disorders characterized by acid reflux, dyspepsia, and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, enhancing patient compliance and symptom control. Izumep Capsule SR is indicated in patients requiring both acid suppression and prokinetic therapy to improve upper gastrointestinal motility and reduce acid exposure. It should be administered as prescribed by a healthcare professional, with caution advised in patients with known hypersensitivity to its components, significant hepatic impairment, or underlying cardiac conditions due to the potential risk of QT interval prolongation associated with Domperidone. Regular monitoring and adherence to recommended dosages are essential to maximize efficacy and minimize adverse effects.
How to use Izumep Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Izumep Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Izumep Capsule SR. Please consult your doctor.
High Risk
Izumep Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Izumep Capsule SR is safe to use in patients with liver disease. No dose adjustment of Izumep Capsule SR is recommended.
Regular Checkup
Izumep Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Izumep Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Izumep Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Izumep Capsule SR















