Itrozac 100 Capsule contains Itraconazole 100 mg, a broad-spectrum antifungal agent belonging to the triazole class. It is primarily indicated for the treatment of various systemic and superficial fungal infections caused by susceptible strains of fungi, including dermatophytes, yeasts, and molds. Itraconazole exerts its antifungal effect by inhibiting the cytochrome P450-dependent enzyme lanosterol 14-α-demethylase, which is essential for the synthesis of ergosterol, a critical component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately fungal cell death. Itrozac 100 is commonly prescribed for conditions such as aspergillosis, histoplasmosis, blastomycosis, onychomycosis, and candidiasis. The capsule formulation allows for convenient oral administration, with absorption enhanced when taken with food. Dosage and duration of therapy depend on the type and severity of infection, as well as patient-specific factors. Caution is advised in patients with hepatic impairment or congestive heart failure, and potential drug interactions should be carefully reviewed due to itraconazole’s effect on cytochrome P450 enzymes. Adverse effects may include gastrointestinal disturbances, headache, rash, and, rarely, hepatotoxicity. Monitoring liver function tests during prolonged therapy is recommended to ensure patient safety.

Dosage & How to Use