Itrobliz 100 Capsule contains Itraconazole 100 mg, a broad-spectrum triazole antifungal agent used for the treatment of various fungal infections. Itraconazole works by inhibiting the cytochrome P450-dependent enzyme lanosterol 14-α-demethylase, which is essential for the conversion of lanosterol to ergosterol, a critical component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately fungal cell death. Itrobliz 100 is indicated for the management of systemic and superficial mycoses, including blastomycosis, histoplasmosis, aspergillosis, onychomycosis, and other dermatophytic infections. The capsule formulation allows for oral administration with improved bioavailability when taken with food. Dosage and duration of therapy depend on the type and severity of infection, and treatment should be guided by clinical response and susceptibility testing. Caution is advised in patients with hepatic impairment, congestive heart failure, or those taking concomitant medications metabolized by the cytochrome P450 system due to potential drug interactions. Common adverse effects include gastrointestinal disturbances, headache, and rash. Regular monitoring of liver function tests is recommended during prolonged therapy. Itrobliz 100 Capsule should be used under medical supervision to ensure efficacy and safety.

Dosage & How to Use