Itocad 100 Injection
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Etoposide (20mg/ml)
Vial of 5 ml • Liquid
A valid prescription is required for this medicine.
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Active composition
Etoposide inhibits topoisomerase II, preventing DNA replication and inducing apoptosis in cancer cells.
Medical applications
Itocad 100 Injection contains Etoposide 20 mg/ml, a semisynthetic podophyllotoxin derivative used primarily as an antineoplastic agent. Itocad 100 is indicated for the treatment of various malignancies, including small cell lung cancer, testicular cancer, lymphomas, and acute myeloid leukemia. Etoposide acts by inhibiting the enzyme topoisomerase II, leading to DNA strand breaks and subsequent apoptosis of rapidly dividing cancer cells.
The injection formulation allows for intravenous administration, ensuring rapid systemic bioavailability and precise dosing in clinical settings. Dosage and duration of therapy should be individualized based on tumor type, patient condition, and response to treatment, with careful monitoring for hematologic toxicity, including neutropenia and thrombocytopenia. Other adverse effects may include alopecia, mucositis, hypotension during infusion, and gastrointestinal disturbances.
Itocad 100 Injection is contraindicated in patients with hypersensitivity to etoposide or any formulation components, and caution is advised in those with impaired hepatic or renal function. Due to its cytotoxic nature, appropriate handling and administration protocols must be followed to minimize exposure risks to healthcare personnel. Regular blood counts and clinical assessments are essential to optimize therapeutic outcomes and manage potential toxicities during treatment with Itocad 100 Injection.
How to use Itocad Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
It is not known whether it is safe to consume alcohol with Itocad 100 Injection. Please consult your doctor.
High Risk
Itocad 100 Injection does not usually affect your ability to drive.
Exercise Caution
Itocad 100 Injection should be used with caution in patients with liver disease. Dose adjustment of Itocad 100 Injection may be needed. Please consult your doctor. Use of Itocad 100 Injection is not recommended in patients with severe liver disease.
Regular Checkup
Itocad 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Itocad 100 Injection should be used with caution in patients with kidney disease. Dose adjustment of Itocad 100 Injection may be needed. Please consult your doctor. Use of Itocad 100 Injection is not recommended in patients with end-stage kidney disease.
Regular Checkup
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