Isozole- DSR Capsule
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Domperidone (30mg) + Esomeprazole (40mg)
1 units • Other
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Isozole-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, indicated for the management of gastroesophageal reflux disease (GERD), erosive esophagitis, and related acid-peptic disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating.
Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, promoting mucosal healing and symptom relief. The synergistic action of these agents provides effective control of acid reflux and improves gastric motility, offering symptomatic relief and mucosal protection. Isozole-DSR is typically administered orally once daily, preferably before meals, with dosage adjustments based on clinical response.
Caution is advised in patients with known hypersensitivity to either component, hepatic impairment, or concurrent use of medications metabolized via CYP3A4 pathways. Common adverse effects may include headache, dry mouth, abdominal discomfort, and dizziness. Isozole-DSR Capsule should be used under medical supervision, ensuring appropriate diagnosis and monitoring for optimal therapeutic outcomes.
How to use Isozole D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isozole- DSR Capsule is to be taken empty stomach.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Caution is advised when consuming alcohol with Isozole- DSR Capsule. Please consult your doctor.
High Risk
Isozole- DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Isozole- DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Isozole- DSR Capsule is recommended.
Regular Checkup
Isozole- DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Isozole- DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Isozole- DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
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