
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Isnafab-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the effective management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing symptomatic relief from acid-related damage and promoting mucosal healing. The synergistic action of these two agents addresses both the underlying hyperacidity and impaired gastric motility often observed in GERD and dyspepsia. Isnafab-DSR is indicated for patients requiring both acid suppression and prokinetic therapy, enhancing overall therapeutic outcomes. It is typically administered orally once daily, preferably before meals, under medical supervision. Caution is advised in patients with known hypersensitivity to either component, underlying cardiac conditions, or hepatic impairment. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. Consultation with a healthcare professional is essential prior to initiation to ensure appropriate use and monitoring.
How to use Isnafab-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isnafab-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Isnafab-DSR Capsule. Please consult your doctor.
High Risk
Isnafab-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Isnafab-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Isnafab-DSR Capsule is recommended.
Regular Checkup
Isnafab-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Isnafab-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Isnafab-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Isnafab-DSR Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Isnafab-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the effective management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing symptomatic relief from acid-related damage and promoting mucosal healing. The synergistic action of these two agents addresses both the underlying hyperacidity and impaired gastric motility often observed in GERD and dyspepsia. Isnafab-DSR is indicated for patients requiring both acid suppression and prokinetic therapy, enhancing overall therapeutic outcomes. It is typically administered orally once daily, preferably before meals, under medical supervision. Caution is advised in patients with known hypersensitivity to either component, underlying cardiac conditions, or hepatic impairment. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. Consultation with a healthcare professional is essential prior to initiation to ensure appropriate use and monitoring.
How to use Isnafab-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isnafab-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Isnafab-DSR Capsule. Please consult your doctor.
High Risk
Isnafab-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Isnafab-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Isnafab-DSR Capsule is recommended.
Regular Checkup
Isnafab-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Isnafab-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Isnafab-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Isnafab-DSR Capsule















