
Domperidone (30mg) + Pantoprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Medical applications
Irazole-DSR Capsule is a combination medication containing Domperidone 30mg and Pantoprazole 40mg, formulated to manage gastrointestinal disorders associated with acid reflux and motility disturbances. Pantoprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, thereby providing symptomatic relief from conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying, which helps alleviate symptoms like nausea, vomiting, bloating, and early satiety. The synergistic action of these two agents addresses both acid-related mucosal damage and delayed gastric emptying, offering comprehensive relief in patients with dyspepsia and reflux symptoms. Irazole-DSR is typically prescribed for short-term use under medical supervision, with dosage adjustments based on clinical response and tolerability. Caution is advised in patients with cardiac conditions due to the potential risk of QT interval prolongation associated with Domperidone. This combination should be used with consideration of contraindications and drug interactions to ensure optimal therapeutic outcomes.
How to use Irazole-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Irazole-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Irazole-DSR Capsule. Please consult your doctor.
High Risk
Irazole-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Irazole-DSR Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Irazole-DSR Capsule may not be needed in these patients. Please consult your doctor.
Regular Checkup
Irazole-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Irazole-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Irazole-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Irazole-DSR Capsule

Domperidone (30mg) + Pantoprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Medical applications
Irazole-DSR Capsule is a combination medication containing Domperidone 30mg and Pantoprazole 40mg, formulated to manage gastrointestinal disorders associated with acid reflux and motility disturbances. Pantoprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, thereby providing symptomatic relief from conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying, which helps alleviate symptoms like nausea, vomiting, bloating, and early satiety. The synergistic action of these two agents addresses both acid-related mucosal damage and delayed gastric emptying, offering comprehensive relief in patients with dyspepsia and reflux symptoms. Irazole-DSR is typically prescribed for short-term use under medical supervision, with dosage adjustments based on clinical response and tolerability. Caution is advised in patients with cardiac conditions due to the potential risk of QT interval prolongation associated with Domperidone. This combination should be used with consideration of contraindications and drug interactions to ensure optimal therapeutic outcomes.
How to use Irazole-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Irazole-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Irazole-DSR Capsule. Please consult your doctor.
High Risk
Irazole-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Irazole-DSR Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Irazole-DSR Capsule may not be needed in these patients. Please consult your doctor.
Regular Checkup
Irazole-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Irazole-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Irazole-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Irazole-DSR Capsule















