Invega Sustenna 75mg Injection
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Paliperidone (75mg)
Prefilled of 1 injection • Other
A valid prescription is required for this medicine.
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Active composition
Paliperidone antagonizes dopamine D2 and serotonin 5-HT2A receptors, restoring neurotransmitter balance and alleviating psychotic symptoms.
Medical applications
Invega Sustenna 75mg Injection contains paliperidone, an atypical antipsychotic agent used primarily for the treatment of schizophrenia and schizoaffective disorder. Administered via intramuscular injection, this long-acting formulation provides sustained therapeutic plasma concentrations, facilitating once-monthly dosing and improving patient adherence. Paliperidone exerts its pharmacological effects by antagonizing dopamine D2 and serotonin 5-HT2A receptors, which helps to restore the neurotransmitter balance implicated in psychotic symptoms.
Invega Sustenna is indicated for the maintenance treatment of schizophrenia in adults and adolescents aged 12 years and older, as well as for schizoaffective disorder as monotherapy or adjunctive therapy with mood stabilizers or antidepressants. The 75mg dose is typically initiated following a recommended titration schedule to achieve optimal plasma levels while minimizing adverse effects.
Common side effects may include extrapyramidal symptoms, weight gain, sedation, and increased prolactin levels. Caution is advised in patients with a history of cardiovascular disease, seizures, or renal impairment. Regular monitoring of metabolic parameters and neurological status is recommended during treatment. Invega Sustenna 75mg Injection offers a convenient and effective option for long-term management of psychotic disorders, enhancing compliance and clinical outcomes.
Benzisoxazole Derivative
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Invega Sustenna 75mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Invega Sustenna 75mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Invega Sustenna 75mg Injection may be needed. Please consult your doctor. Use of Invega Sustenna 75mg Injection is not recommended in patients with end-stage kidney disease.
Exercise Caution
Invega Sustenna 75mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Invega Sustenna 75mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Invega Sustenna 75mg Injection may be needed. Please consult your doctor. Limited information is available on the use of Invega Sustenna 75mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
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