Introcid-D Capsule SR
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Domperidone (30mg) + Rabeprazole (20mg)
1 units • Other
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Introcid-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30mg and Rabeprazole 20mg, designed for the effective management of gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility by enhancing esophageal and gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating.
Rabeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing symptomatic relief in acid-related conditions. The sustained-release (SR) formulation ensures prolonged therapeutic plasma concentrations, improving patient compliance and efficacy. Introcid-D Capsule SR is indicated for the treatment of gastroesophageal reflux disease (GERD), functional dyspepsia, peptic ulcer disease, and other acid-peptic disorders where both acid suppression and prokinetic action are beneficial.
It is contraindicated in patients with known hypersensitivity to either component, and caution is advised in those with cardiac arrhythmias or prolactinoma due to Domperidone’s potential side effects. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. Introcid-D Capsule SR should be administered under medical supervision, with dosage adjustments based on clinical response and patient tolerance.
How to use Introcid-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Introcid-D Capsule SR is to be taken empty stomach.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Caution is advised when consuming alcohol with Introcid-D Capsule SR. Please consult your doctor.
High Risk
Introcid-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Introcid-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Introcid-D Capsule SR may be needed. Please consult your doctor. Use of Introcid-D Capsule SR is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Introcid-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Introcid-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Introcid-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
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