
Levosulpiride (75mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Insapraz-LSR Capsule is a combination pharmaceutical formulation containing Levosulpiride 75 mg and Esomeprazole 40 mg, indicated for the management of gastroesophageal reflux disease (GERD), functional dyspepsia, and other acid-related gastrointestinal disorders. Levosulpiride, a selective dopamine D2 receptor antagonist, facilitates gastric motility and enhances esophageal sphincter tone, thereby improving gastric emptying and reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related mucosal damage and promoting healing of erosive esophagitis. The synergistic action of these two agents addresses both motility dysfunction and acid hypersecretion, offering comprehensive symptom control. Insapraz-LSR is typically administered orally once daily before meals, with dosage adjustments based on clinical response and tolerability. Caution is advised in patients with hepatic impairment, and it is contraindicated in individuals with known hypersensitivity to either component. Common adverse effects may include headache, dizziness, and mild gastrointestinal disturbances. This combination therapy should be used under medical supervision to optimize therapeutic outcomes and minimize potential risks.
How to use Insapraz-L Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Insapraz-LSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Insapraz-LSR Capsule.
High Risk
Insapraz-LSR Capsule may cause side effects which could affect your ability to drive. Insapraz-LSR Capsule may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
Exercise Caution
Insapraz-LSR Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Insapraz-LSR Capsule may be needed. Please consult your doctor.
Regular Checkup
Insapraz-LSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Insapraz-LSR Capsule in patients with kidney disease. Please consult your doctor. However, limited data suggest a cautious use of this medicine in these patients.
Regular Checkup
0 reviews for Insapraz-LSR Capsule

Levosulpiride (75mg) + Esomeprazole (40mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Insapraz-LSR Capsule is a combination pharmaceutical formulation containing Levosulpiride 75 mg and Esomeprazole 40 mg, indicated for the management of gastroesophageal reflux disease (GERD), functional dyspepsia, and other acid-related gastrointestinal disorders. Levosulpiride, a selective dopamine D2 receptor antagonist, facilitates gastric motility and enhances esophageal sphincter tone, thereby improving gastric emptying and reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related mucosal damage and promoting healing of erosive esophagitis. The synergistic action of these two agents addresses both motility dysfunction and acid hypersecretion, offering comprehensive symptom control. Insapraz-LSR is typically administered orally once daily before meals, with dosage adjustments based on clinical response and tolerability. Caution is advised in patients with hepatic impairment, and it is contraindicated in individuals with known hypersensitivity to either component. Common adverse effects may include headache, dizziness, and mild gastrointestinal disturbances. This combination therapy should be used under medical supervision to optimize therapeutic outcomes and minimize potential risks.
How to use Insapraz-L Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Insapraz-LSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Insapraz-LSR Capsule.
High Risk
Insapraz-LSR Capsule may cause side effects which could affect your ability to drive. Insapraz-LSR Capsule may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
Exercise Caution
Insapraz-LSR Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Insapraz-LSR Capsule may be needed. Please consult your doctor.
Regular Checkup
Insapraz-LSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Insapraz-LSR Capsule in patients with kidney disease. Please consult your doctor. However, limited data suggest a cautious use of this medicine in these patients.
Regular Checkup
0 reviews for Insapraz-LSR Capsule















