
Domperidone (30mg) + Rabeprazole (20mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Insakool-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Rabeprazole 20mg, designed for the management of gastrointestinal disorders. Domperidone is a peripheral dopamine D2 receptor antagonist that enhances gastrointestinal motility by increasing the movement of the stomach and intestines, thereby facilitating gastric emptying and reducing symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor, suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The combination of Domperidone and Rabeprazole in Insakool-DSR Capsule offers synergistic therapeutic benefits by addressing both motility and acid secretion abnormalities, making it suitable for patients experiencing dyspepsia, acid reflux, and other functional gastrointestinal disorders. This medication should be used under medical supervision, with attention to contraindications such as known hypersensitivity to either component, prolactinoma, or severe hepatic impairment. Common adverse effects may include headache, dry mouth, or gastrointestinal disturbances. Insakool-DSR Capsule is typically administered orally, and dosage should be individualized based on clinical response and tolerability.
How to use Insakool-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Insakool-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Insakool-DSR Capsule. Please consult your doctor.
High Risk
Insakool-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Insakool-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Insakool-DSR Capsule may be needed. Please consult your doctor. Use of Insakool-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Insakool-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Insakool-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Insakool-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Insakool-DSR Capsule

Domperidone (30mg) + Rabeprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Insakool-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Rabeprazole 20mg, designed for the management of gastrointestinal disorders. Domperidone is a peripheral dopamine D2 receptor antagonist that enhances gastrointestinal motility by increasing the movement of the stomach and intestines, thereby facilitating gastric emptying and reducing symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor, suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The combination of Domperidone and Rabeprazole in Insakool-DSR Capsule offers synergistic therapeutic benefits by addressing both motility and acid secretion abnormalities, making it suitable for patients experiencing dyspepsia, acid reflux, and other functional gastrointestinal disorders. This medication should be used under medical supervision, with attention to contraindications such as known hypersensitivity to either component, prolactinoma, or severe hepatic impairment. Common adverse effects may include headache, dry mouth, or gastrointestinal disturbances. Insakool-DSR Capsule is typically administered orally, and dosage should be individualized based on clinical response and tolerability.
How to use Insakool-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Insakool-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Insakool-DSR Capsule. Please consult your doctor.
High Risk
Insakool-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Insakool-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Insakool-DSR Capsule may be needed. Please consult your doctor. Use of Insakool-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Insakool-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Insakool-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Insakool-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
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