Impurose 5 Tablet
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Rosuvastatin (5mg)
Strip of 10 tablets • Tablet
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Active composition
Rosuvastatin inhibits HMG-CoA reductase, decreasing cholesterol synthesis in the liver and increasing LDL receptor expression.
Medical applications
Impurose 5 Tablet contains Rosuvastatin 5 mg, a potent lipid-lowering agent belonging to the statin class of medications. It is primarily indicated for the treatment of hypercholesterolemia and mixed dyslipidemia to reduce elevated total cholesterol, low-density lipoprotein cholesterol (LDL-C), apolipoprotein B, and triglycerides, while increasing high-density lipoprotein cholesterol (HDL-C).
Rosuvastatin acts by selectively inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, thereby decreasing cholesterol production in the liver and enhancing clearance of LDL particles from the bloodstream. This mechanism contributes to the prevention of atherosclerotic cardiovascular disease, including coronary heart disease, stroke, and peripheral arterial disease.
Impurose 5 is indicated as an adjunct to diet and lifestyle modifications, such as exercise and weight control, to achieve optimal lipid levels. It may also be used in patients with primary dysbetalipoproteinemia and homozygous familial hypercholesterolemia. Dosage should be individualized based on patient response and risk factors, with regular monitoring of lipid profiles and liver function tests recommended.
Common adverse effects include headache, myalgia, and gastrointestinal disturbances. Caution is advised in patients with hepatic impairment and those on concomitant medications that may increase the risk of myopathy.
Phenylpyrimidine derivatives
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Impurose 5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
High Risk
Impurose 5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Medical Advice
Impurose 5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Impurose 5 Tablet may be needed. Please consult your doctor. Use of Impurose 5 Tablet is not recommended in patients with severe kidney disease.
Exercise Caution
Impurose 5 Tablet does not usually affect your ability to drive.
Consult Doctor
Impurose 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Impurose 5 Tablet may be needed. Please consult your doctor. Use of Impurose 5 Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
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